Iwao Takanami, MD, Ken Takeuchi, MD, Masatoshi Giga, MD

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Presentation transcript:

The prognostic value of natural killer cell infiltration in resected pulmonary adenocarcinoma Iwao Takanami, MD, Ken Takeuchi, MD, Masatoshi Giga, MD The Journal of Thoracic and Cardiovascular Surgery Volume 121, Issue 6, Pages 1058-1063 (June 2001) DOI: 10.1067/mtc.2001.113026 Copyright © 2001 American Association for Thoracic Surgery Terms and Conditions

Fig. 1 A and B show immunohistochemical staining of pulmonary adenocarcinoma with IOT-10 (CD57) monoclonal antibody. Positive cells are identified in the stroma of the tumor (arrowhead). Photographs of pulmonary adenocarcinoma show a negative control, a low level, and a high level of NK-cell infiltration. (A : original magnification 200×; B , C , and D : original magnification 80×.) The Journal of Thoracic and Cardiovascular Surgery 2001 121, 1058-1063DOI: (10.1067/mtc.2001.113026) Copyright © 2001 American Association for Thoracic Surgery Terms and Conditions

Fig. 2 Overall survival curves of the patients with pulmonary adenocarcinoma on the basis of NK cell infiltration. A significant difference was seen between the 2 groups (P =.0002). The Journal of Thoracic and Cardiovascular Surgery 2001 121, 1058-1063DOI: (10.1067/mtc.2001.113026) Copyright © 2001 American Association for Thoracic Surgery Terms and Conditions

Fig. 3 Survival curves of the patients with stage I pulmonary adenocarcinoma on the basis of NK classification. A significant difference was seen between the 2 groups (P =.049). The Journal of Thoracic and Cardiovascular Surgery 2001 121, 1058-1063DOI: (10.1067/mtc.2001.113026) Copyright © 2001 American Association for Thoracic Surgery Terms and Conditions

Fig. 4 Survival curves of the patients with stage II pulmonary adenocarcinoma on the basis of NK classification. A significant difference was not seen between the 2 groups (P =.3). The Journal of Thoracic and Cardiovascular Surgery 2001 121, 1058-1063DOI: (10.1067/mtc.2001.113026) Copyright © 2001 American Association for Thoracic Surgery Terms and Conditions

Fig. 5 Survival curves of the patients with stage III pulmonary adenocarcinoma on the basis of NK classification. A significant difference was not seen between the 2 groups (P =.8). The Journal of Thoracic and Cardiovascular Surgery 2001 121, 1058-1063DOI: (10.1067/mtc.2001.113026) Copyright © 2001 American Association for Thoracic Surgery Terms and Conditions