This Month in Gastroenterology

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Presentation transcript:

This Month in Gastroenterology Jan Tack, John M. Carethers  Gastroenterology  Volume 138, Issue 7, Pages 2191-2194 (June 2010) DOI: 10.1053/j.gastro.2010.04.017 Copyright © 2010 AGA Institute Terms and Conditions

Figure 1 Rates of complications in those patients undergoing either laparoscopic or open operations for diverticular disease stratified according to risk predictors. (A) Stratification into three groups of probability of morbidity. (B) Patients stratified according to ASA classification. Differences in rates of complications are statistically significant in both figures. Gastroenterology 2010 138, 2191-2194DOI: (10.1053/j.gastro.2010.04.017) Copyright © 2010 AGA Institute Terms and Conditions

Figure 2 Conversion rate and recurrent biliary events with early or delayed LC after ES. The prevalence of recurrent biliary events is significantly higher after delayed LC (P <.001). Gastroenterology 2010 138, 2191-2194DOI: (10.1053/j.gastro.2010.04.017) Copyright © 2010 AGA Institute Terms and Conditions

Figure 3 TTC37 is composed of 43 exons. The position of each of the mutations from 12 THES syndrome patients is shown in this schematic drawing. The TPR domains in relation to the exons and mutations are shown in blue. Gastroenterology 2010 138, 2191-2194DOI: (10.1053/j.gastro.2010.04.017) Copyright © 2010 AGA Institute Terms and Conditions

Figure 4 Thrombocytopenic mice show exacerbated liver fibrosis after bile duct ligation treatment. Bcl-xflox/floxPf4-Cre (KO) and bcl-xflox/flox mice were sham operated or subjected to bile duct ligation and analyzed 10 days later (8–12 mice per group). (Upper panels) Liver fibrosis was evaluated by picrosirius red staining of liver sections and total hydroxyproline levels. (Lower panels) The co1a1 and col1a2 mRNA levels in the liver were determined by real-time reverse transcriptase polymerase chain reaction. Expression of type I collagen protein in the liver was assessed by Western blotting. Gastroenterology 2010 138, 2191-2194DOI: (10.1053/j.gastro.2010.04.017) Copyright © 2010 AGA Institute Terms and Conditions