Volume 151, Issue 6, Pages (December 2016)

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Volume 151, Issue 6, Pages 1113-1121 (December 2016) Repeat Treatment With Rifaximin Is Safe and Effective in Patients With Diarrhea- Predominant Irritable Bowel Syndrome Anthony Lembo, Mark Pimentel, Satish S. Rao, Philip Schoenfeld, Brooks Cash, Leonard B. Weinstock, Craig Paterson, Enoch Bortey, William P. Forbes Gastroenterology Volume 151, Issue 6, Pages 1113-1121 (December 2016) DOI: 10.1053/j.gastro.2016.08.003 Copyright © 2016 AGA Institute Terms and Conditions

Figure 1 Study design (A) and mean baseline IBS symptom severity for patients entering the open-label treatment phase versus the same patients entering the double-blind, first repeat treatment phase (n = 636) (B). DB, double-blind; EOS, end of study; IBS, irritable bowel syndrome; OL, open-label; SC, stool sample collection time point. Gastroenterology 2016 151, 1113-1121DOI: (10.1053/j.gastro.2016.08.003) Copyright © 2016 AGA Institute Terms and Conditions

Figure 2 Change from baseline in average daily abdominal pain scores during the first and second repeat treatment double-blind phases. aStatistically significant difference vs placebo. Data were analyzed using last observation carried forward methodology. Gastroenterology 2016 151, 1113-1121DOI: (10.1053/j.gastro.2016.08.003) Copyright © 2016 AGA Institute Terms and Conditions