From Shellfish Poisoning to Neuroscience

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From Shellfish Poisoning to Neuroscience Azadeh Shahsavar, Thomas Balle Structure Volume 23, Issue 6, Pages 979-980 (June 2015) DOI: 10.1016/j.str.2015.05.008 Copyright © 2015 Elsevier Ltd Terms and Conditions

Figure 1 Chemical and 3D Structures of Pinnatoxins (A) Chemical structure of PnTx-A and PnTx-G. (B) 3D structure of PnTx-A. The structure is extracted from PnTx-A/Ac-AChBP X-ray structure (PDB: 4XHE). Structure 2015 23, 979-980DOI: (10.1016/j.str.2015.05.008) Copyright © 2015 Elsevier Ltd Terms and Conditions

Figure 2 Overall Structure of PnTx-A Bound to Ac-AChBP, PDB: 4XHE The principal and complementary subunits are shown in slate and light teal, respectively. PnTx-A is colored green, and residues in vicinity of the ligand-binding site that generally vary between subunits and between nAChRs and AChBPs are colored red. Structure 2015 23, 979-980DOI: (10.1016/j.str.2015.05.008) Copyright © 2015 Elsevier Ltd Terms and Conditions