Systemic effects of carbon dioxide insufflation technique for de-airing in left-sided cardiac surgery  Maya Landenhed, MD, Faleh Al-Rashidi, MD, PhD,

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Systemic effects of carbon dioxide insufflation technique for de-airing in left-sided cardiac surgery  Maya Landenhed, MD, Faleh Al-Rashidi, MD, PhD, Sten Blomquist, MD, PhD, Peter Höglund, MD, PhD, Leif Pierre, EBCP, Bansi Koul, MD, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 147, Issue 1, Pages 295-300 (January 2014) DOI: 10.1016/j.jtcvs.2012.11.010 Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Arterial blood gases and extracorporeal gas dynamics before, during, and at the end of cardiopulmonary bypass (CPB). Circles indicate the carbon dioxide group, triangles indicate the Lund group. PaCO2, Partial pressure of carbon dioxide; VCO2, volume of carbon dioxide produced. *P < .05; **P < .01; ***P < .001 for between-group comparisons. The Journal of Thoracic and Cardiovascular Surgery 2014 147, 295-300DOI: (10.1016/j.jtcvs.2012.11.010) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Cerebral hemodynamics measured by transcranial Doppler (TCD) and regional cerebral oxygen saturation (rSO2) measured by near-infrared spectroscopy before, during, and at end of cardiopulmonary bypass (CPB). Circles indicate carbon dioxide group, triangles indicate Lund group. *P < .05; **P < .01; ***P < .001 for between-group comparisons. The Journal of Thoracic and Cardiovascular Surgery 2014 147, 295-300DOI: (10.1016/j.jtcvs.2012.11.010) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 A, Scanning electron microscope pictures of the cardiotomy and/or left ventricular vent tubings showing morphology of the red blood cells in the carbon dioxide group. B, Scanning electron microscope pictures of the cardiotomy and/or left ventricular vent tubings showing morphology of the red blood cells in the Lund group. The fraction of damaged red cells in the carbon dioxide group was 0.97 compared with 0.18 in the Lund group. The Journal of Thoracic and Cardiovascular Surgery 2014 147, 295-300DOI: (10.1016/j.jtcvs.2012.11.010) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions