Fat digestion modulates gastrointestinal sensations induced by gastric distention and duodenal lipid in humans  Christine Feinle, Thomas Rades, Bärbel Otto, Michael Fried  Gastroenterology  Volume 120, Issue 5, Pages 1100-1107 (April 2001) DOI: 10.1053/gast.2001.23232 Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 1 Gastric volume changes in response to intestinal infusions at MDP. Data are means ± SEM. Significant differences *from respective THL condition, §from MCT, and #from SPE; P < 0.05. Gastroenterology 2001 120, 1100-1107DOI: (10.1053/gast.2001.23232) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 2 Scores for nausea, fullness, pressure/pain, hunger, and bloating during isobaric gastric distention and duodenal infusion of the fat emulsions. Data are means ± SEM. Significant differences *from respective THL condition, §from MCT, and #from SPE; P < 0.05. Gastroenterology 2001 120, 1100-1107DOI: (10.1053/gast.2001.23232) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 3 Maximally tolerated pressures during gastric distention and duodenal infusion of LCT, LCT-THL, MCT, MCT-THL, or SPE. Data are means ± SEM. Significant differences *from respective THL conditions, §from MCT, and #from SPE; P < 0.05. Gastroenterology 2001 120, 1100-1107DOI: (10.1053/gast.2001.23232) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 4 Plasma CCK responses to duodenal infusion of the fat emulsions and gastric distention. LCT-THL, LCT containing the lipase inhibitor THL; MCT-THL, MCT containing THL. Data are means ± SEM. *Significantly different from all other conditions, P < 0.05. Gastroenterology 2001 120, 1100-1107DOI: (10.1053/gast.2001.23232) Copyright © 2001 American Gastroenterological Association Terms and Conditions