Effect of Intercurrent Operation and Cerebral Oxygenation on Developmental Trajectory in Congenital Heart Disease  George M. Hoffman, MD, Cheryl L. Brosig,

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Effect of Intercurrent Operation and Cerebral Oxygenation on Developmental Trajectory in Congenital Heart Disease  George M. Hoffman, MD, Cheryl L. Brosig, PhD, Laurel M. Bear, MD, James S. Tweddell, MD, Kathleen A. Mussatto, PhD  The Annals of Thoracic Surgery  Volume 101, Issue 2, Pages 708-716 (February 2016) DOI: 10.1016/j.athoracsur.2015.08.059 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Change in Bayley Scales of Infant and Toddler Development 3rd Edition (BSID-III) scores over time by patient diagnostic category of 1 ventricle (1V, blue), 2 ventricles (2V, red), and genetic syndrome (GS, green). The linear mixed-effect model parameter estimates and 95% confidence intervals are shown as symbols and range bars. The Annals of Thoracic Surgery 2016 101, 708-716DOI: (10.1016/j.athoracsur.2015.08.059) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Effect of interval open cardiac procedures (red) compared with no open procedures (blue) on neurodevelopmental trajectories. The fixed-effect model parameter estimates and 95% confidence intervals are shown as symbols and range bars. (BSID-III = Bayley Scales of Infant and Toddler Development 3rd Edition.) The Annals of Thoracic Surgery 2016 101, 708-716DOI: (10.1016/j.athoracsur.2015.08.059) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions