Calcitonin and Omega–3 Fatty Acids Exhibit Antagonistic and Non-Additive Effects in Experimental Diabetes  Wale Johnson Adeyemi, Luqman Aribidesi Olayaki 

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Calcitonin and Omega–3 Fatty Acids Exhibit Antagonistic and Non-Additive Effects in Experimental Diabetes  Wale Johnson Adeyemi, Luqman Aribidesi Olayaki  Pathophysiology  Volume 25, Issue 2, Pages 117-123 (June 2018) DOI: 10.1016/j.pathophys.2018.02.003 Copyright © 2018 Elsevier B.V. Terms and Conditions

Fig. 1 Effects of Sct and/or N-3 on total alkaline phosphatase (TALP) in streptozotocin + nicotinamide – induced diabetes mellitus in male Wistar rats. Values (n = 5) across the column are expressed as mean ± SEM. *p < 0.05 is significant compared to control; #p < 0.05 is significant compared to diabetic untreated; cp < 0.05 is significant – D + Sct.Lw vs D + Sct.Hi ep < 0.05 is significant – D + Sct.Hi vs D + N-3 + Sct.Hi. Pathophysiology 2018 25, 117-123DOI: (10.1016/j.pathophys.2018.02.003) Copyright © 2018 Elsevier B.V. Terms and Conditions

Fig. 2 Effects of Sct and/or N-3 on collagen type 2 alpha 1(C2M) in streptozotocin + nicotinamide – induced diabetes mellitus in male Wistar rats. Values (n = 5) across the column are expressed as mean ± SEM. *P < 0.05 is significant compared to control; #p < 0.05 is significant compared to diabetic untreated. Pathophysiology 2018 25, 117-123DOI: (10.1016/j.pathophys.2018.02.003) Copyright © 2018 Elsevier B.V. Terms and Conditions

Fig. 3 Effects of Sct and/or N-3 on c-telopeptide of type I collagen (CTX-1) in streptozotocin + nicotinamide – induced diabetes mellitus in male Wistar rats. Values (n = 5) across the column are expressed as mean ± SEM. *p < 0.05 is significant compared to control; #p < 0.05 is significant compared to diabetic untreated. Pathophysiology 2018 25, 117-123DOI: (10.1016/j.pathophys.2018.02.003) Copyright © 2018 Elsevier B.V. Terms and Conditions