Prevalence and histopathology of chronic polypoid sinusitis in pediatric patients with cystic fibrosis  Sebastian P. Schraven, Manfred Wehrmann, Wolfgang.

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Presentation transcript:

Prevalence and histopathology of chronic polypoid sinusitis in pediatric patients with cystic fibrosis  Sebastian P. Schraven, Manfred Wehrmann, Wolfgang Wagner, Gunnar Blumenstock, Assen Koitschev  Journal of Cystic Fibrosis  Volume 10, Issue 3, Pages 181-186 (May 2011) DOI: 10.1016/j.jcf.2011.01.003 Copyright © 2011 European Cystic Fibrosis Society. Terms and Conditions

Fig. 1 Histologic findings of the glandular parenchyma in CPS in CF versus non-CF patients. Mucous glandular parenchyma (A, arrow) with dilated glandular ducts was typical for CF patients. Serous glandular structures (B, arrow) were observed in non-CF patients. Scale bars A and B, 500μm. Journal of Cystic Fibrosis 2011 10, 181-186DOI: (10.1016/j.jcf.2011.01.003) Copyright © 2011 European Cystic Fibrosis Society. Terms and Conditions

Fig. 2 Cell populations in CPS in CF and non-CF patients. Eosinophils (A) were found in significant higher number in non-CF patients; on the other hand the number of plasma cells (B) and mast cells (C) in sinunasal polyps was significant higher in CF patients. Approximately equal numbers of CD8+ positive lymphocytes (D) were found in non-CF and CF patients. Scale bars A–D, 100μm. Journal of Cystic Fibrosis 2011 10, 181-186DOI: (10.1016/j.jcf.2011.01.003) Copyright © 2011 European Cystic Fibrosis Society. Terms and Conditions

Fig. 3 Histologic findings of vascularisation in CPS in CF and non-CF patients. The examination of vascularisation pattern, visualized with CD31+ revealed no significant different between non-CF and CF patients. Scale bar, 500μm. Journal of Cystic Fibrosis 2011 10, 181-186DOI: (10.1016/j.jcf.2011.01.003) Copyright © 2011 European Cystic Fibrosis Society. Terms and Conditions