Comparison of complexity metrics for multi-institutional evaluations of treatment plans in radiotherapy  Victor Hernandez, Jordi Saez, Marlies Pasler,

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Comparison of complexity metrics for multi-institutional evaluations of treatment plans in radiotherapy  Victor Hernandez, Jordi Saez, Marlies Pasler, Diego Jurado-Bruggeman, Nuria Jornet  Physics and Imaging in Radiation Oncology  Volume 5, Pages 37-43 (January 2018) DOI: 10.1016/j.phro.2018.02.002 Copyright © 2018 The Authors Terms and Conditions

Fig. 1 Scatter plots for four pairs of complexity indices. Data corresponds to audit plans for the same mock cases. The shaded areas in (b) correspond to linear fits of the head and neck and prostate cases separately taking into account data from all treatment planning systems. The shaded area in (d) corresponds to a linear fit to the data for TPS-A plans regardless of the treatment site. Physics and Imaging in Radiation Oncology 2018 5, 37-43DOI: (10.1016/j.phro.2018.02.002) Copyright © 2018 The Authors Terms and Conditions

Fig. 2 Spearman’s correlation coefficients and their statistical significance p and false discovery rates q for the (a) head-and-neck and (b) prostate plans from the audit. Statistically significant correlations are marked (*) and coded in colour. Physics and Imaging in Radiation Oncology 2018 5, 37-43DOI: (10.1016/j.phro.2018.02.002) Copyright © 2018 The Authors Terms and Conditions

Fig. 3 Box plots showing (a) the mean dose rate variations and (b) the mean gantry speed variations for the audit plans and the three treatment planning systems evaluated. The central line indicates the median value, the box limits represent the 1st and 3rd quartile and the whiskers indicate the minimum and maximum values. Physics and Imaging in Radiation Oncology 2018 5, 37-43DOI: (10.1016/j.phro.2018.02.002) Copyright © 2018 The Authors Terms and Conditions

Fig. 4 Dose rate and gantry speed as a function of the gantry angle for plans from TPS-B (top) and TPS-A (bottom). Data from log files and predictions from the emulator are given for two representative plans corresponding to the same head-and-neck case. Physics and Imaging in Radiation Oncology 2018 5, 37-43DOI: (10.1016/j.phro.2018.02.002) Copyright © 2018 The Authors Terms and Conditions

Fig. 5 The comparison between MItotal and EM is shown for (a) head-and-neck and (b) prostate clinical plans. In (c) and (d) the corresponding mean gantry speed and mean dose rate variations are shown. Physics and Imaging in Radiation Oncology 2018 5, 37-43DOI: (10.1016/j.phro.2018.02.002) Copyright © 2018 The Authors Terms and Conditions