Volume 15, Issue 10, Pages e253-e274 (October 2018)

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Volume 15, Issue 10, Pages e253-e274 (October 2018) Systematic review for the 2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death Fred M. Kusumoto, MD, FACC, Kent R. Bailey, PhD, Ahmad Sami Chaouki, MD, PhD, Abhishek J. Deshmukh, MBBS, Sandeep Gautam, MD, MPH, Robert J. Kim, MD, Daniel B. Kramer, MD, MPH, Litsa K. Lambrakos, MD, FACC, Naseer H. Nasser, MD, Dan Sorajja, MD Heart Rhythm Volume 15, Issue 10, Pages e253-e274 (October 2018) DOI: 10.1016/j.hrthm.2017.10.037 Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 1.1 PRISMA Diagram Demonstrating Selection of Studies Included in the Meta-analysis. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 1.2 Forest Plot for Risk of All Arrhythmic Events Excluding Brugada et al. (2003).10 RE = random effects. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 1.3 Forest Plot for Risk of All Arrhythmic Events Including Brugada et al. (2003).10 RE = random effects. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 1.4 Funnel Plot for Risk of All Arrhythmic Events Excluding Brugada et al. (2003).10 Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 1.5 Funnel Plot for Risk of All Arrhythmic Events Including Brugada et al. (2003).10 Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.1 PRISMA Diagram for ICD Prevention in Older Patients. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.2 PRISMA Diagram for ICD Prevention in Patients With Significant Comorbidities (Including Renal). Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.3 Forest Plot for ICD Implantation in Older Patients. ICD = implantable cardioverter-defibrillator; RE = random effects. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.4 Funnel Plot for ICD Implantation in Older Patients. ICD = implantable cardioverter-defibrillator. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.5 Forest Plot for ICD Implantation in Older Patients (Minimal Overlap). ICD = implantable cardioverter-defibrillator; RE = random effects. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.6 Funnel Plot ICD Implantation in Older Patients (Minimal Overlap). ICD = implantable cardioverter-defibrillator. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.7 Forest Plot for ICD Implantation in Patients With Significant Comorbidities. ICD = implantable cardioverter-defibrillator; RE = random effects. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.8 Forest Plot for ICD Implantation in Patients With Significant Comorbidities (Minimal Overlap). ICD = implantable cardioverter-defibrillator; RE = random effects. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.9 Funnel Plot for ICD Implantation in Patients With Significant Comorbidities. ICD = implantable cardioverter-defibrillator. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.10 Funnel Plot for ICD Implantation in Patients With Significant Comorbidities (Minimal Overlap). ICD = implantable cardioverter-defibrillator. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.11 Forest Plot for ICD Implantation in Patient With Renal Comorbidities. ICD = implantable cardioverter-defibrillator; RE = random effects. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions

Figure 2.12 Funnel Plot for ICD Implantation in Patient With Renal Comorbidities. ICD = implantable cardioverter-defibrillator. Heart Rhythm 2018 15, e253-e274DOI: (10.1016/j.hrthm.2017.10.037) Copyright © 2018 American College of Cardiology Foundation, the American Heart Association, Inc., and the Heart Rhythm Society Terms and Conditions