Reversal of the Anticoagulant Effects of Warfarin by Vitamin K1

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Presentation transcript:

Reversal of the Anticoagulant Effects of Warfarin by Vitamin K1 Jack Hirsh, MD, FCCP CHEST Volume 114, Issue 6, Pages 1505-1508 (December 1998) DOI: 10.1378/chest.114.6.1505 Copyright © 1998 The American College of Chest Physicians Terms and Conditions

FIGURE 1 Vitamin K1 is reduced to Vitamin KH2 by two warfarin-sensitive enzymes (KO-reductase to K-reductase) and the nicotinamide adenine dinucleotide dependent reductase system that is insensitive to warfarin. CHEST 1998 114, 1505-1508DOI: (10.1378/chest.114.6.1505) Copyright © 1998 The American College of Chest Physicians Terms and Conditions