Loss of αv Integrin Expression and Recurrence in Node-Negative Lung Carcinoma W.Roy Smythe, Dahlia Wasfi, Joseph E Bavaria, Steven M Albelda, Larry R.

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Presentation transcript:

Loss of αv Integrin Expression and Recurrence in Node-Negative Lung Carcinoma W.Roy Smythe, Dahlia Wasfi, Joseph E Bavaria, Steven M Albelda, Larry R Kaiser The Annals of Thoracic Surgery Volume 64, Issue 4, Pages 949-953 (October 1997) DOI: 10.1016/S0003-4975(97)00851-5

Fig. 1 Photomicrograph of normal bronchial epithelium with underlying non–small cell lung carcinoma (adenocarcinoma). Note strong (red) immunostaining with αv monoclonal antibody at both the progenitor bronchial epithelium and the tumor cells. (NBE = normal bronchial epithelium; S = submucosal tissue; TC = tumor cells.) (×100 before 40% reduction.) The Annals of Thoracic Surgery 1997 64, 949-953DOI: (10.1016/S0003-4975(97)00851-5)

Fig. 2 Percentage of non–small cell lung carcinoma specimens from patients with negative nodes that exhibited downregulation or complete loss of αv expression versus the recurrence of non–small cell lung carcinoma during the clinical follow-up period. The Annals of Thoracic Surgery 1997 64, 949-953DOI: (10.1016/S0003-4975(97)00851-5)