Expert Perspectives in the Recognition and Management of Lennox-Gastaut Syndrome.

Slides:



Advertisements
Similar presentations
What to do IF Medications Fail? Dr Linda Huh Pediatric Neurologist BCCH.
Advertisements

Eduardo Garcia, MD Assistant Clinical Professor
Anti Epileptic Drugs (AEDs) Sampath Charya, MD, FAAN, FAASM VAMC, Fayetteville, NC.
Lennox Gastaut Syndrome Enrique Feoli MD North East Regional Epilepsy Group.
Transition from Pediatric to Adult Care
Recent Advances in the Diagnosis and Treatment of Epilepsy
Anticonvulsants By Alaina Darby.
CBZ is the most common antiepileptic drug (AED) causing AED-induced seizure worsening. CBZ can both aggravate and induce new seizure types including absence,
Evolving Standards in HER2-Targeted Adjuvant Therapy for Breast Cancer
Moderate-to-Severe Asthma Management
New Psoriasis Treatments
Psoriatic Arthritis.
Pharmaceutical- vs Dispensary-Sourced Cannabinoids
Exploring the Spectrum of Excessive Daytime Sleepiness
Progression After Cancer Immunotherapy in Advanced NSCLC
Reducing Postoperative Ileus
Understanding the Many Faces of Pseudobulbar Affect
Ask the Onychomycosis Expert, Part 2
Standards of Care in Duchenne Muscular Dystrophy: A 2018 Update
Improving Acne Outcomes
Neurostimulation for the Management of Medication-Resistant Epilepsy
Case Challenges in Chronic Migraine
Updates in Management of Atopic Dermatitis From Real Patient Cases
Definitions: Seizure, Epilepsy, Epilepsy Syndrome
Advances in Dry Eye.
Before and After: Patient Cases in Onychomycosis
Induction Chemotherapy for Patients With High-Risk or Secondary AML
Management Considerations in Epilepsy Among Long-Term Care Residents
Determining the Best Treatment Algorithm for Patients With Head and Neck Cancer.
Transition of Care in Epilepsy Among Patients Entering Long-Term Care
Chronic Idiopathic Urticaria
Treatment of Generalized Tonic-Clonic Seizures in the Modern Era
Expert Tips for Tackling Atopic Dermatitis in Pediatric Practice
Asthma and Atopic Comorbidities
Updates in Neuronal Ceroid Lipofuscinosis
A Frontline Clinician's Guide to Managing Opioid-Induced Constipation
Seizures in the Elderly: Treatment and Special Considerations
Multidisciplinary Perspectives on Interstitial Lung Diseases
Management of Adolescents With Seizures
This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the US, and data that were.
Case Studies in Unresectable Hepatocellular Carcinoma
Hyperhidrosis Is Burdensome!
Gene Therapy: Past, Present, and Future
Tackling Atopic Dermatitis
Ask the Experts.
Immunotherapy for cSCC
CGRP Antibodies in Migraine
Optimizing Frontline Care for Older Patients With Multiple Myeloma
Introduction. Exploring Strategies for Recognition and Management of Lower Limb Spasticity in Children.
Best Practices in the Clinical Management of Motor Symptoms Associated With Huntington Disease.
Best Practices in the Identification and Management of Alzheimer Agitation.
When Is Biologic Therapy Appropriate for HS?
Personalizing Management in the Care of Patients With Advanced Sarcoma
Expert Perspectives on the Clinical Use of Immune Reconstitution vs Escalation Therapy for MS.
Updates in Seizure Management
Advances in Immunotherapy for Peanut Allergy
Understanding and Addressing the Needs of Patients With AD
Guide to Atopic Dermatitis
This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the US, and data that were.
EGPA.
The Burden of Psoriasis:
Updates in Neuronal Ceroid Lipofuscinosis
Patient Questions and Expert Answers in Psoriasis:
Evaluating BTK Inhibitors in CLL
Patient and Clinician Perspectives on Preventive Therapy for Migraine
Novel Concepts in the Management of RCC
Issues in Patients With Severe Epilepsy
PAH Pathways: What Do the Data Tell Us?”
This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the US, and data that were.
Introduction. Welcome to this program, titled De-Escalating Therapy in Epilepsy: A Return to Monotherapy.
Presentation transcript:

Expert Perspectives in the Recognition and Management of Lennox-Gastaut Syndrome

This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the United States.

Introduction to LGS

Epidemiology of LGS

Epidemiology of LGS (cont)

Symptom Presentation

Atonic-Clonic Seizure

Tonic Seizure

Tonic Seizure Symptomatic Generalized Epilepsy

LGS Triad

EEG Findings in LGS

Differential Diagnosis

Evaluation

EEG Characteristics

Treatment Goals

Treatment Options

Pharmacologic Treatment

FDA-Approved Pharmacologic Treatment for LGS*

Felbamate: Adjunctive Therapy

Lamotrigine: Adjunctive Therapy

Topiramate: Adjunctive Therapy

Rufinamide: Adjunctive Therapy

Clobazam: Adjunctive Therapy

Challenges in the Treatment of LGS

Ketogenic Diet

Corpus Callosotomy

Vagus Nerve Stimulation

Investigational Treatment: Perampanel

Investigational Treatment: Cannabidiol

Comorbidities in LGS

Transition to Care by an Adult Neurologist

Conclusions

Abbreviations