Prolonged preservation of the blood-perfused canine heart with glycolysis-promoting solution Koh Takeuchi, MD, Hung Cao-Danh, PhD, Akihiko Kawai, MD,

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Prolonged preservation of the blood-perfused canine heart with glycolysis-promoting solution Koh Takeuchi, MD, Hung Cao-Danh, PhD, Akihiko Kawai, MD, Akihiko Ohkado, MD, Hiroaki Konishi, MD, Francis X McGowan, MD, Pedro J del Nido, MD The Annals of Thoracic Surgery Volume 68, Issue 3, Pages 903-907 (September 1999) DOI: 10.1016/S0003-4975(99)00534-2

Fig 1 Peak developed pressure at a diastolic pressure of 15 mm Hg in control hearts (nonischemic) and after 2 hours of reperfusion in hearts subjected to 24 hours of 4°C ischemia receiving histidine-buffered solution (HBS) or University of Wisconsin solution (UWS). ∗p < 0.05 between HBS and UWS groups. The Annals of Thoracic Surgery 1999 68, 903-907DOI: (10.1016/S0003-4975(99)00534-2)

Fig 2 Peak systolic pressure at different balloon volumes in hearts subjected to 24 hours of 4°C ischemia receiving histidine-buffered solution (closed circles) or University of Wisconsin solution (open circles). Top, After 1 hour (left) and 2 hours (right) of reperfusion. Bottom, In the presence of low-dose (0.2 mg/L, left) or high-dose (1 mg/L, right) dobutamine in the perfusate. ∗p < 0.05 between groups. The Annals of Thoracic Surgery 1999 68, 903-907DOI: (10.1016/S0003-4975(99)00534-2)

Fig 3 End-diastolic pressure at different balloon volumes in hearts subjected to 24 hours of 4°C ischemia receiving histidine-buffered solution (closed circles) or University of Wisconsin solution (open circles). Top, After 1 hour (left) and 2 hours (right) of reperfusion. Bottom, In the presence of low-dose (0.2 mg/L, left) or high-dose (1 mg/L, right) dobutamine in the perfusate. ∗p < 0.05 between groups. The Annals of Thoracic Surgery 1999 68, 903-907DOI: (10.1016/S0003-4975(99)00534-2)

Fig 4 End-diastolic volume at a diastolic pressure of 15 mm Hg in control hearts (nonischemic) and hearts subjected to 24 hours of 4°C ischemia receiving histidine-buffered solution (HBS) or University of Wisconsin solution (UWS). There were no significant differences between control and HBS. ∗p < 0.05 between groups. The Annals of Thoracic Surgery 1999 68, 903-907DOI: (10.1016/S0003-4975(99)00534-2)