Corticosteroid use and bone mineral accretion in children with asthma: Effect modification by vitamin D  Sze Man Tse, MDCM, H. William Kelly, PharmD,

Slides:



Advertisements
Similar presentations
Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing Danielle C.M. Belgrave, MSc,
Advertisements

Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy Yitzhak Katz, MD, Nelly Rajuan, MSc, Michael R. Goldberg,
Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.
Endoplasmic reticulum stress influences bronchial asthma pathogenesis by modulating nuclear factor κB activation So Ri Kim, MD, PhD, Dong Im Kim, MS, Mi.
The Pediatric Asthma Control and Communication Instrument asthma questionnaire: For use in diverse children of all ages  Sande O. Okelo, MD, PhD, Michelle.
What drives prescription patterns in pediatric asthma management?
Advances in Diagnosing Peanut Allergy
Fatty acids, inflammation, and asthma
A cluster-randomized trial to provide clinicians inhaled corticosteroid adherence information for their patients with asthma  L. Keoki Williams, MD, MPH,
Sunita Sharma, MD, MPH, Augusto Litonjua, MD, MPH 
Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD 
Vitamin D supplementation in pregnancy, prenatal 25(OH)D levels, race, and subsequent asthma or recurrent wheeze in offspring: Secondary analyses from.
Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study  John M. Brehm, MD, MPH, Brooke Schuemann, BS,
Is 9 more than 2 also in allergic airway inflammation?
Fatty acids, inflammation, and asthma
Joe K. Gerald, MD, PhD, Roni Grad, MD, William C. Bailey, MD, Lynn B
Genetic and histologic evidence for autophagy in asthma pathogenesis
The Pediatric Asthma Control and Communication Instrument asthma questionnaire: For use in diverse children of all ages  Sande O. Okelo, MD, PhD, Michelle.
Rising prevalence of asthma is sex-specific in a US farming population
Lieuwe D. Bos, MSc, PhD, Peter J. Sterk, MD, PhD, Stephen J
Test for Respiratory and Asthma Control in Kids (TRACK): A caregiver-completed questionnaire for preschool-aged children  Kevin R. Murphy, MD, Robert.
Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts  Heung-Woo Park, MD, PhD,
Vitamin D levels and food and environmental allergies in the United States: Results from the National Health and Nutrition Examination Survey  
Physician needs in health informatics: Just ask the docs
Advances in Diagnosing Peanut Allergy
Peter M. Wolfgram, MD, David B. Allen, MD 
William J. Calhoun, MD, Tmirah Haselkorn, PhD, Dave P
An age-dependent association of mannose-binding lectin-2 genetic variants on HIV-1– related disease in children  Kumud K. Singh, PhD, Alexis Lieser, MD,
The HEDIS Medication Management for People with Asthma Measure is Not Related to Improved Asthma Outcomes  Angelina Crans Yoon, MD, William Crawford,
Jewlya Lynn, PhD, Sophie Oppenheimer, MS, MPH, Lorena Zimmer, MA 
Penicillin Skin Testing Is a Safe and Effective Tool for Evaluating Penicillin Allergy in the Pediatric Population  Stephanie J. Fox, MD, Miguel A. Park,
Reply Journal of Allergy and Clinical Immunology
Polymorphisms of chitinases are not associated with asthma
Risk of congenital malformations for asthmatic pregnant women using a long-acting β2- agonist and inhaled corticosteroid combination versus higher-dose.
Intranasal triamcinolone use during pregnancy and the risk of adverse pregnancy outcomes  Anick Bérard, MSc, PhD, Odile Sheehy, MSc, Marie-Laure Kurzinger,
Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation  Leif Bjermer, MD  Journal of Allergy.
What are the best outcome measurements for atopic eczema
Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management  Scott H. Sicherer, MD, Hugh A. Sampson, MD  Journal.
Biosimilars and drug development in allergic and immunologic diseases
Daphne Koinis-Mitchell, PhD, Timothy Craig, DO, Cynthia A
A cluster-randomized trial shows telephone peer coaching for parents reduces children's asthma morbidity  Jane M. Garbutt, MB, ChB, Yan Yan, MD, PhD,
Claus Bachert, MD, PhD, Cezmi A. Akdis, MD 
What is an “eosinophilic phenotype” of asthma?
Cephalosporin Side Chain Cross-reactivity
The widening black/white gap in asthma hospitalizations and mortality
H. William Kelly, PharmD  Journal of Allergy and Clinical Immunology 
Autophagy: Nobel Prize 2016 and allergy and asthma research
Higher incidence of pediatric anaphylaxis in northern areas of the United States  William J. Sheehan, MD, Dionne Graham, PhD, Lin Ma, MS, Sachin Baxi,
Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment
Advances in the approach to the patient with food allergy
Diagnosis and management of early asthma in preschool-aged children
Inhaled corticosteroid treatment modulates ZNF432 gene variant’s effect on bronchodilator response in asthmatics  Ann Chen Wu, MD, MPH, Blanca E. Himes,
Geographic variability in childhood asthma prevalence in Chicago
A single intervention for cockroach control reduces cockroach exposure and asthma morbidity in children  Felicia A. Rabito, PhD, MPH, John C. Carlson,
Mary F. Linehan, PhD, Timothy L. Frank, MD, Michelle L
Genome-wide expression profiles identify potential targets for gene-environment interactions in asthma severity  Joanne E. Sordillo, ScD, MS, Roxanne.
Corinne A. Keet, MD, MS, Wayne G. Shreffler, MD, PhD, Roger D
Prevention of food allergy: Beyond peanut
Acid-suppressive drug use in pregnancy and the toddler's asthma risk: A crossover, case-control study  Bianca Mulder, BSc, Catharina Carolina Maria Schuiling-Veninga,
Jessica H. Savage, MD, MHS, Elizabeth C. Matsui, MD, MHS, Robert A
Measles and immunomodulation
A longitudinal analysis of wheezing in young children: The independent effects of early life exposure to house dust endotoxin, allergens, and pets  Augusto.
Consumer attitudes and risks associated with packaged foods having advisory labeling regarding the presence of peanuts  Susan L. Hefle, PhD, Terence J.
Macrolide antibiotics and asthma treatment
Asthma: The past, future, environment, and costs
Asthma Control Test: Reliability, validity, and responsiveness in patients not previously followed by asthma specialists  Michael Schatz, MD, MS, Christine.
Environmental factors and eosinophilic esophagitis
Advances in pediatric asthma in 2007
Natural history of cow’s milk allergy
Primary prevention of asthma and allergy
Presentation transcript:

Corticosteroid use and bone mineral accretion in children with asthma: Effect modification by vitamin D  Sze Man Tse, MDCM, H. William Kelly, PharmD, Augusto A. Litonjua, MD, MPH, Mark L. Van Natta, MHS, Scott T. Weiss, MD, MS, Kelan G. Tantisira, MD, MPH  Journal of Allergy and Clinical Immunology  Volume 130, Issue 1, Pages 53-60.e4 (July 2012) DOI: 10.1016/j.jaci.2012.04.005 Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Difference in BMA between OCS-exposed and OCS-unexposed boys by category of OCS exposure and vitamin D sufficiency status. Vitamin D–insufficient boys who were exposed to more than 2 OCS courses per year had twice the difference in BMA compared with that seen in vitamin D–sufficient boys. Journal of Allergy and Clinical Immunology 2012 130, 53-60.e4DOI: (10.1016/j.jaci.2012.04.005) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions