Comparison of KRAS Mutation Analysis and FISH for Detecting Pancreatobiliary Tract Cancer in Cytology Specimens Collected During Endoscopic Retrograde.

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Presentation transcript:

Comparison of KRAS Mutation Analysis and FISH for Detecting Pancreatobiliary Tract Cancer in Cytology Specimens Collected During Endoscopic Retrograde Cholangiopancreatography Benjamin R. Kipp, Emily G. Barr Fritcher, Amy C. Clayton, Gregory J. Gores, Lewis R. Roberts, Jun Zhang, Michael J. Levy, Kevin C. Halling The Journal of Molecular Diagnostics Volume 12, Issue 6, Pages 780-786 (November 2010) DOI: 10.2353/jmoldx.2010.100016 Copyright © 2010 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 1 Specimen-processing flowchart, illustrating how pancreatobiliary samples were processed for routine clinical testing and KRAS mutation analysis. The Journal of Molecular Diagnostics 2010 12, 780-786DOI: (10.2353/jmoldx.2010.100016) Copyright © 2010 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 2 Representative examples of normal and abnormal FISH and KRAS testing results. The Journal of Molecular Diagnostics 2010 12, 780-786DOI: (10.2353/jmoldx.2010.100016) Copyright © 2010 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 3 Frequency of specific KRAS mutations detected by qPCR. The Journal of Molecular Diagnostics 2010 12, 780-786DOI: (10.2353/jmoldx.2010.100016) Copyright © 2010 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions