Outcomes of contemporary mechanical circulatory support device configurations in patients with severe biventricular failure Allison P. Levin, BA, MSc,

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Presentation transcript:

Outcomes of contemporary mechanical circulatory support device configurations in patients with severe biventricular failure Allison P. Levin, BA, MSc, Natalia Jaramillo, MD, A. Reshad Garan, MD, Koji Takeda, MD, PhD, Hiroo Takayama, MD, Melana Yuzefpolskaya, MD, Donna M. Mancini, MD, Yoshifumi Naka, MD, PhD, Paolo C. Colombo, MD, Veli K. Topkara, MD, MSc The Journal of Thoracic and Cardiovascular Surgery Volume 151, Issue 2, Pages 530-535.e2 (February 2016) DOI: 10.1016/j.jtcvs.2015.10.019 Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Postimplantation survival in patients requiring CF-LVAD versus BiVAD support. CI, Confidence interval; CF-LVAD, continuous-flow left ventricular assist device; BiVAD, biventricular assist device; HR, hazard ratio. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 530-535.e2DOI: (10.1016/j.jtcvs.2015.10.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 BiVAD preference, based on geographic region. East = regions 1, 2, and 9; Midwest = regions 7, 8, and 10; South = regions 3, 4, and 11; and West = regions 5 and 6. Values within bars are n within region and device categories, Biventricular assist device; CF-BiVAD, continuous-flow BiVAD; TAH, total artificial heart; PF-BiVAD, pulsatile-flow biventricular assist device; paraRVAD, paracorporeal right ventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 530-535.e2DOI: (10.1016/j.jtcvs.2015.10.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Postimplantation survival on BiVAD, based on device type. CI, Confidence interval; TAH, total artificial heart; BiVAD, biventricular assist device; CF-BiVAD, continuous-flow BiVAD; paraRVAD, paracorporeal right ventricular assist device; PF-BiVAD, pulsatile-flow biventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 530-535.e2DOI: (10.1016/j.jtcvs.2015.10.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Postimplantation survival on BiVAD, based on BSA quartile. CI, Confidence interval; BSA, body surface area. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 530-535.e2DOI: (10.1016/j.jtcvs.2015.10.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 Identification of the analysis cohort from the UNOS database. MCS, Mechanical circulatory support; UNOS, United Network for Organ Sharing; LVAD, left ventricular assist device; RVAD, right ventricular assist device; BiVAD, biventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 530-535.e2DOI: (10.1016/j.jtcvs.2015.10.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure E2 Changing trends in use of BiVAD types. CF-BiVAD, Continuous-flow biventricular assist device; PF-BiVAD, pulsatile-flow biventricular assist device; TAH, total artificial heart; paraRVAD, paracorporeal right ventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 530-535.e2DOI: (10.1016/j.jtcvs.2015.10.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure E3 A, Bridge-to-transplantation rate; (B) Posttransplantation survival of patients with various BiVAD types. TAH, Total artificial heart; CF-BiVAD, continuous-flow biventricular assist device; paraRVAD, paracorporeal right ventricular assist device; PF-BiVAD, pulsatile-flow biventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 530-535.e2DOI: (10.1016/j.jtcvs.2015.10.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Postimplantation survival on BiVADS. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 530-535.e2DOI: (10.1016/j.jtcvs.2015.10.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions