Supplementary Table 1.

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Presentation transcript:

Supplementary Table 1

Supplementary Figure 1 A-954248 A-962653 A-1155905 A-1208746 A-1210477 A-1248767

MCL-1-NOXA BCL-2-BIM BCL-XL-BCL-XS Supplementary Figure 2 Mammalian Two-Hybrid MCL-1-NOXA BCL-2-BIM BCL-XL-BCL-XS % Complex Remaining A-1155905 (mM) A-1155905 (mM) A-1155905 (mM)

a Supplementary Figure 3 0 min 5 min 10 min 30 min 90 min Overlay DMSO BIMS(2A)DC mCherry- Overlay 10 mM A-1210477 BIMS(2A)DC mCherry- eGFP-MCL-1(3B)

b Supplementary Figure 3 0 min 5 min 10 min 30 min 90 min Overlay DMSO mCherry-BAD Overlay 10 mM A-1210477 mCherry-BAD eGFP-BCL-XL

c Supplementary Figure 3 0 min 5 min 10 min 30 min 90 min Overlay DMSO mCherry-BAD Overlay 10 mM A-1210477 mCherry-BAD eGFP-BCL-2

Bak-/- Bax-/- MEFs Supplementary Figure 4 A-1155905 A-1208746 staurosporine bortezomib