Unveiling the molecular basis of antimicrobial resistance in Staphylococcus aureus from the Democratic Republic of the Congo using whole genome sequencing

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Unveiling the molecular basis of antimicrobial resistance in Staphylococcus aureus from the Democratic Republic of the Congo using whole genome sequencing P. Phaku, M. Lebughe, L. Strauß, G. Peters, M. Herrmann, D. Mumba, A. Mellmann, J.-J. Muyembe-Tamfum, F. Schaumburg Clinical Microbiology and Infection Volume 22, Issue 7, Pages 644.e1-644.e5 (July 2016) DOI: 10.1016/j.cmi.2016.04.009 Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 1 Passaging of OS-MRSA on subinhibitory oxacillin concentrations. Nine OS-MRSA from DRC were passaged on Müller-Hinton agar with gradient of oxacillin (0–2 mg/L). Oxacillin MIC was measured after each passage (positive control, ATCC 43300; negative control, ATCC 29213). Median (range) oxacillin is shown for nine OS-MRSAs. After second passage, all isolates were within resistance range. Susceptibility range (≤2 mg/L) is shaded in grey. Clinical Microbiology and Infection 2016 22, 644.e1-644.e5DOI: (10.1016/j.cmi.2016.04.009) Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions