EGFR Exon 19 Insertions Show Good Response to Gefitinib, but Short Time to Progression in Japanese Patients Jangchul Park, MD, Chiaki Kondo, MD, Junichi.

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EGFR Exon 19 Insertions Show Good Response to Gefitinib, but Short Time to Progression in Japanese Patients Jangchul Park, MD, Chiaki Kondo, MD, Junichi Shimizu, MD, PhD, Yoshitsugu Horio, MD, PhD, Kimihide Yoshida, MD, PhD, Toyoaki Hida, MD, PhD Journal of Thoracic Oncology Volume 9, Issue 2, Pages e10-e11 (February 2014) DOI: 10.1097/JTO.0b013e3182a735cc Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Computed tomography scan of chest: (A) before treatment; (B) 2 months after treatment with gefitinib. Journal of Thoracic Oncology 2014 9, e10-e11DOI: (10.1097/JTO.0b013e3182a735cc) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Mutant form of epidermal growth factor receptor insertion (I744_K745 ins KIPVAI) in exon 19 was identified by reverse transcription-polymerase chain reaction coupled with direct sequencing. Arrow shows nucleotide transition from C to T. Journal of Thoracic Oncology 2014 9, e10-e11DOI: (10.1097/JTO.0b013e3182a735cc) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions