Figure 1 Structure and composition of the brush border

Slides:

Advertisements

Similar presentations

H3 Absorption of digested foods

Advertisements

Cell Adhesion and Extracellular Matrix. Cells in tissues can adhere directly to one another (cell–cell adhesion) through specialized integral membrane.

Online Counseling Resource YCMOU ELearning Drive… School of Architecture, Science and Technology Yashwantrao Chavan Maharashtra Open University, Nashik.

Cell Motility and Shape require microfilaments (F-actin), microtubules and intermediate filaments. Not surprisingly, the actin skeleton is dynamic, not.

Cell-cell adhesion occurs through morphological structures and CAMs.

Tissues Cells work together in functionally related groups called tissues How is this done? Attachments Communication Types of tissues: 1. Epithelial –

The Cytoskeleton... Is a supportive meshwork of fine fibers inside eukaryotic cells Provides structural support Is involved in cell movement and movement.

The cytoskeleton, mitochondrial bioenergetics and apoptosis Professor Daniel C. Hoessli March 2013.

Cytology 244 First Term of year Nuha AL-Abdulhadi lab 4

Dr Mah Jabeen Muneera Assistant Professor Department of Anatomy KEMU.

Tissues & Junctions Lecture 34 Chapter 21 - Part 1.

Ch. 4 Part 1 Tissues and Junctions.

Lecture 3 Stratified Epithelium. 2 SQUAMOUSCUBOIDALCOLUMNARTRANSITIONAL COMPOUND EPITHELIA Stratified columnar epithelia are rare; they are sometimes.

Sticky Business Mirna Perez-Moreno, Colin Jamora, Elaine Fuchs Cell

Figure 4 Intercalated disc maturation

Figure 4 Activation of clopidogrel via cytochrome P450

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Figure 1 Gut microorganisms at the intersection of several diseases

Figure 5 Lipid droplet consumption

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

درس دوم اسکلت سلولی و ضمائم تحرک سلول ها

Volume 5, Issue 6, Pages (June 2009)

Figure 3 Histological subtypes of intrahepatic CCA

Some of the pictures presented in this lecture are taken from

Figure 4 Giant lipid droplet formation

Figure 1 The components of the intercalated disc

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Figure 6 Combination therapy for HCC

Figure 2 Switching of biologic agents and biosimilars

Desmosomes: New Perspectives on a Classic

Figure 3 Example wireless motility recording

to the liver and promote patient-derived xenograft tumour growth

Figure 7 Example colonic high-resolution manometry

Figure 1 Environmental factors contributing to IBD pathogenesis

Figure 2 13C-octanoic acid gastric emptying breath test

Volume 3, Issue 4, Pages (October 2002)

in the UK (1961–2012), France (1961–2014) and Italy (1961–2010)

Figure 2 Three distinct paracellular epithelial

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Figure 5 High-resolution manometry studies performed

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Figure 2 New therapeutic approaches in IBD with their specific targets

Volume 13, Issue 6, Pages R215-R216 (March 2003)

Nat. Rev. Cardiol. doi: /nrcardio

Figure 2 The hypoxia-induced proinflammatory

Intestinal epithelial barrier.

Actin Waves: Origin of Cell Polarization and Migration?

Figure 4 Local species pools that contribute to the

Epithelial Contractility: A Crowning Achievement

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

A Hitchhiker's Guide to Mechanobiology

Overview of structural and functional mechanisms by which enterovirulent bacteria cause diarrhea. Overview of structural and functional mechanisms by which.

Figure 1 New therapeutic approaches in IBD therapy based on blockade of T-cell homing and retention Figure 1 | New therapeutic approaches in IBD therapy.

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Exploring the Neighborhood

Figure 2 Lifelong influences on the gut microbiome from

Volume 37, Issue 6, Pages (June 2016)

A Gate Keeper for Axonal Transport

Tensile Forces and Mechanotransduction at Cell–Cell Junctions

Volume 84, Issue 3, Pages (February 1996)

Epithelia Tissue Epithelia can be divided into two main groups:

Figure 8 Assessment of colonic tone using a barostat device

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Actin-Based Cell Motility and Cell Locomotion

Two Poles and a Compass Cell

Excerpts of identified gene expression profiles.

Presentation transcript:

Figure 1 Structure and composition of the brush border Figure 1 | Structure and composition of the brush border. The brush border is composed of two interconnected regions, the microvillus assembly and the terminal web area. Structure and composition of the microvilli and the underlying terminal web are shown (1). Adhesion complexes are localted at the brush border, such as tight junctions, adherens junctions and desmosomes. Whether EpCAM is part of a precise adhesion complex is not currently known. Contractile forces are generated by the actomyosin network (black arrows) and actively contribute to brush border contraction and shape modulation. Microvillus clustering occurs via physical links provided by protocadherins (2). The 'treadmilling' phenomenon constitutes a dynamic equilibrium between actin polymerization at the tip of the microvillus (barbed end) and actin depolymerization at the actin rootlet (pointed end) (3). This process helps to maintain the microvillus at constant length, but also provides the required forces to push the plasma membrane and drive microvillus formation (black arrows). AJ, adherens junction; CDHR2, cadherin-related family member-2 (also known as protocadherin-24); EB-3, microtubule-associated protein RP/EB family member 3; EpCAM, epithelial cell adhesion molecule; MLPCDH, mucin-like protocadherin; TJ, tight junction. Delacour, D. et al. (2016) Plasticity of the brush border — the yin and yang of intestinal homeostasis Nat. Rev. Gastroenterol. Hepatol. doi:10.1038/nrgastro.2016.5