Tommy L. Lewis, Franck Polleux Neuron

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Presentation transcript:

Neuronal Morphogenesis: Golgi Outposts, Acentrosomal Microtubule Nucleation, and Dendritic Branching Tommy L. Lewis, Franck Polleux Neuron Volume 76, Issue 5, Pages 862-864 (December 2012) DOI: 10.1016/j.neuron.2012.11.019 Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 1 Golgi Outpost-Associated Microtubule Nucleation Sites Regulate Distal Dendritic Branching In nonneuronal cells (left panel), both centrosome-associated and Golgi-associated acentrosomal microtubule nucleation sites coexist around the nucleus. In large and complex cells such neurons (right panel), in addition to these microtubule nucleation sites present in the cell body, Golgi-outpost-associated acentrosomal MT nucleation sites are distributed throughout the dendritic tree where they regulate microtubule dynamics and dendritic branch stability. Neuron 2012 76, 862-864DOI: (10.1016/j.neuron.2012.11.019) Copyright © 2012 Elsevier Inc. Terms and Conditions