High-frequency oscillatory ventilation and an interventional lung assist device to treat hypoxaemia and hypercapnia  David M. , Heinrichs W.   British Journal of Anaesthesia  Volume 93, Issue 4, Pages 582-586 (October 2004) DOI: 10.1093/bja/aeh231 Copyright © 2004 British Journal of Anaesthesia Terms and Conditions

Fig 1 Time course of P a 2 (kPa)/ F   2 ratio and oxygenation index (mean airway pressure× F   2 ×100/ P a 2 (mm Hg)) after initiation of HFOV. Data are given as mean (sem) of measurements/day. The P a 2 / F   2 ratio increased with HFOV initiation. Oxygenation was unchanged after the patient was returned to PCV, and then changed to pressure support ventilation (PSV). The oscillatory frequency during HFOV was increased from 3.5 to 9 Hz and oscillatory amplitude was decreased from 95 to 25 cm H2O after initiation of ILA. Despite higher adjusted mean airway pressures during HFOV, the oxygenation index decreased. British Journal of Anaesthesia 2004 93, 582-586DOI: (10.1093/bja/aeh231) Copyright © 2004 British Journal of Anaesthesia Terms and Conditions

Fig 2 Time course of P a 2 during the 15 days after admission, and measured passive blood flow and adjusted gas flow (oxygen) of the ILA system. Data are mean (sem) of measurements/day. P a 2 decreased with HFOV but increased again on day 2. Reduced oscillatory frequencies, increased oscillatory amplitudes and a higher bias flow of the HFOV had no influence on P a 2 . After ILA initiation, P a 2 decreased and was maintained at the lower level. Mean passive blood flow of the ILA ranged from 1.9 to 2.4 litre min−1. Adjusted oxygen flow of the ILA was reduced in steps. British Journal of Anaesthesia 2004 93, 582-586DOI: (10.1093/bja/aeh231) Copyright © 2004 British Journal of Anaesthesia Terms and Conditions