Haploidentical Transplantation Using T Cell Replete Peripheral Blood Stem Cells and Myeloablative Conditioning in Patients with High-Risk Hematologic.

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Presentation transcript:

Haploidentical Transplantation Using T Cell Replete Peripheral Blood Stem Cells and Myeloablative Conditioning in Patients with High-Risk Hematologic Malignancies Who Lack Conventional Donors is Well Tolerated and Produces Excellent Relapse-Free Survival: Results of a Prospective Phase II Trial Scott R. Solomon, Connie A. Sizemore, Melissa Sanacore, Xu Zhang, Stacey Brown, H. Kent Holland, Lawrence E. Morris, Asad Bashey Biology of Blood and Marrow Transplantation Volume 18, Issue 12, Pages 1859-1866 (December 2012) DOI: 10.1016/j.bbmt.2012.06.019 Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Posttransplantation fever curves. Points represent the Tmax of individual patients for the preceding 24 hours. Biology of Blood and Marrow Transplantation 2012 18, 1859-1866DOI: (10.1016/j.bbmt.2012.06.019) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Cumulative incidence of (A) acute graft-versus-host disease (GVHD) and (B) chronic GVHD. Biology of Blood and Marrow Transplantation 2012 18, 1859-1866DOI: (10.1016/j.bbmt.2012.06.019) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Probability of (A) overall and disease-free survival and (B) relapse and nonrelapse mortality. Biology of Blood and Marrow Transplantation 2012 18, 1859-1866DOI: (10.1016/j.bbmt.2012.06.019) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions