Hematological problems

Slides:



Advertisements
Similar presentations
Limitations in FIX Measurement and Inhibitor Testing Silvana Spiteri, Kevin Vella, Alex Gatt Introduction Haemophilia B (Christmas disease) is characterised.
Advertisements

Sex-Linked Traits Most traits of the human genome are autosomal traits, which means the alleles for these traits are located on pairs 1 –22. Some traits.
Pedigrees.
MISHA MAZHAR 2k10-NUST-BS-V&I-54.  Mutations in F8 or F9 genes.  Leads to lack of proteins made by these genes.  F8 responsible for making the blood.
List at least 3 genetic conditions you know of. Why do you think they are genetic conditions?
Hemophilia A By Marissa Miuccio.
Pedigree definition  Pedigree: a family history that shows how a trait is inherited over several generations  Pedigrees are usually used when parents.
Sarah Moreno Ms.Brown Child dev. -6
All will know which chromosomes make a boy and which chromosomes make a girl. Most will be able to explain what a genetic counsellor is. Some will understand.
Sex linked genes.
Child with hematological dysfunction Emad Al Khatib, RN,MSN,CNS.
Amanda Gee Jessica Meah AP Biology - 3
Haemophilia The bleeding disorder. Amna Ghazali. The Nature of Haemophilia Haemophilia is a hereditary disorder; meaning people are affected from birth.
Sex Linked Inheritance
Sex Linked Inheritance A human female, has 23 pair of chromosomes A human male, has 22 similar pairs and one pair consisting of two chromosomes that are.
Quiz 7E Variations in Mendel's Theories Sex-linked Traits.
Hemophilia A By Saad Mukaty. Definition of Hemophilia  Hemophilia (A) is a rare disorder in which blood doesn’t clot normally because it lacks important.
Hemophilia Hadeeth Zaidi Period 6. What it does/Causes -The disease (only present in males) lowers the level of blood plasma clotting factors which are.
Haemophilia This presentation is by group 2 Welcome Haemophilia is a inherited and lifelong blood disorder where an essential blood clotting factor is.
Hemophilia By Charlene Yan.
Genetic Screening and Counselling
Human Genetic Disorders Every cell in the human body has 46 chromosomes except for gametes, egg sperm cells, which contain 23 or the haploid number. Human.
Unit 2 – Pedigrees.
Hemophilia By: Olivia Holman, Oscar Sierras Jaimes and Daniel Barnett.
Hemophilia in Canis familiaris (dogs). General information MIM number: MIM number: MIA number: MIA number:
Bleeding disorders Deficiency of any of the clotting factors leads to excessive bleeding Most common and important bleeding disorders are due Vitamin K.
Approach To Bleeding Disorders In Neonates
Haemophilia Haemophilia is a disorder which can be identified by the body’s inability to control blood clotting, which leads to frequent haemorrhages,
NEONATAL IMMUNE THROMBOCYTOPENIA
Autosomal & Sex-Linked Pedigrees
HEMOPHELIA.
How Can You Study Human Heredity?
NAME______________________ Hematology Case Study due in class on entry. Hematology/Immune Case Study in Preparation for class is required an worth two.
GENETICS & HEREDITY.
Pedigrees in Human Genetics
Unit 3.
Chapter 2 Supplementary Classification:
October 30, 2015 TO DO: Notebook, pencil/pen WARM UP: HOMEWORK:
The Xs and Ys of Genetics
GENETICS & HEREDITY.
Hemophilia.
INHERITED GENETIC DISORDERS
Chromosomes, Autosomes and Sex chromosomes
Genetic Counselling.
by Walter H. A. Kahr, and Yigal Dror
Sex-linked Traits.
Different mode and types of inheritance
A family history of a genetic condition
Congenital bleeding disorders
Human Genetic Disorders Part 3
Tracing Traits Pedigrees.
Sex-linked Traits Using punnett squares.
The Xs and Ys of Genetics
X-Linked Inheritance (Sex Linked)
Hemophilia Genetics of the F8C Gene.
Pre-conceptual health and care
Complete Station Race Assignment…
GENETICS & HEREDITY.
Passing Through the Generations: How to Read a Pedigree
Class Notes #8: Genetic Disorders
The child with hematological dysfunction
GENETICS & HEREDITY.
Inheritance - Pedigrees
Pedigrees.
Hemophilia Genetics of the F8C Gene.
The Xs and Ys of Genetics
Sex-Linked Traits and Chromosomal Disorders
Pedigree Notes Family history that shows how a trait is inherited over ____________ generations. Carriers: those ____________ for a trait. Can determine.
X-Linked Inheritance (Sex Linked)
Presentation transcript:

Hematological problems Ayda khader Feb . 2018

Bleeding Bleeding is generally rare in the newborn, there are a small number of significant conditions that can result in bleeding of which the midwife should be aware. Blood from the gastrointestinal tract (vomiting or passed per rectum as malaena) is sometimes seen and the commonest cause is swallowed maternal blood. This is supported if there is a clear history of maternal bleeding and bloodstained amniotic fluid. The baby should be carefully evaluated and the possibility of bleeding from the gastrointestinal tract considered. This could occur if there was a clottng or platelet abnormality, or occasionally with some serious gastrointestinal disorders such as NEC.

Possible causes of bleeding abnormalities Vitamin K-deficient bleeding (VKDB) Thrombocytopenia  Haemophilia and other inherited problems

Haemophilia Haemophilia A is an X-linked recessive disorder, which therefore affects only boys. Females may be carriers. diagnosis is often known or suspected antenatally because of a family history. investigation should occur after birth IM injections and invasive procedures should be avoided. The diagnosis can be made by checking a clotting profile should always be considered in a male baby who has unexpected bleeding.

Thanks