Volume 2, Issue 3, Pages (May 2016)

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Volume 2, Issue 3, Pages 224-226 (May 2016) Photo-induced drug eruption in a patient on combination simeprevir/sofosbuvir for hepatitis C  Zachary W. Eyre, BS, Aaron M. Secrest, MD, PhD, Jamie L. Woodcock, MD, MS  JAAD Case Reports  Volume 2, Issue 3, Pages 224-226 (May 2016) DOI: 10.1016/j.jdcr.2016.03.007 Copyright © 2016 Terms and Conditions

Fig 1 Photo-distributed eruption in a patient on simeprevir. The patient presented with a large erosion of the lower vermilion with honey-colored and hemorrhagic crusting (A) and ill-defined erythematous plaques with overlying tense bullae on the dorsolateral hands (B). JAAD Case Reports 2016 2, 224-226DOI: (10.1016/j.jdcr.2016.03.007) Copyright © 2016 Terms and Conditions

Fig 2 Histopathology shows spongiotic dermatitis with marked papillary dermal edema and a perivascular infiltrate of composed of lymphocytes, few neutrophils, and rare eosinophils. (A and B, Hematoxylin-eosin stain; original magnifications: A, ×100 and B, ×200.) JAAD Case Reports 2016 2, 224-226DOI: (10.1016/j.jdcr.2016.03.007) Copyright © 2016 Terms and Conditions