Performance of Busulfan Dosing Guidelines for Pediatric Hematopoietic Stem Cell Transplant Conditioning Jamie H. Zao, Tal Schechter, Wenchao Jessica.

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Performance of Busulfan Dosing Guidelines for Pediatric Hematopoietic Stem Cell Transplant Conditioning Jamie H. Zao, Tal Schechter, Wenchao Jessica Liu, Sandra Gerges, Adam Gassas, R. Maarten Egeler, Eyal Grunebaum, L. Lee Dupuis Biology of Blood and Marrow Transplantation Volume 21, Issue 8, Pages 1471-1478 (August 2015) DOI: 10.1016/j.bbmt.2015.05.006 Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Box plot of AUCs achieved after simulated i.v. busulfan dosing using 12 dosing guidelines in 97 children with TBW/IBW < 1.25. Note: the bottom and top edges of each box indicate the 25th and 75th percentiles. The center horizontal line is drawn at the median. Vertical lines are drawn from the box to the most extreme point within 1.5 interquartile ranges. The mean is indicated by a diamond. Values outside this range are marked with an open circle. Biology of Blood and Marrow Transplantation 2015 21, 1471-1478DOI: (10.1016/j.bbmt.2015.05.006) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions