Perioperative management with antiplatelet and statin medication is associated with reduced mortality following vascular surgery Randall R. De Martino,

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Perioperative management with antiplatelet and statin medication is associated with reduced mortality following vascular surgery Randall R. De Martino, MD, MS, Jens Eldrup-Jorgensen, MD, Brian W. Nolan, MD, MS, David H. Stone, MD, Julie Adams, MD, Daniel J. Bertges, MD, Jack L. Cronenwett, MD, Philip P. Goodney, MD, MS Journal of Vascular Surgery Volume 59, Issue 6, Pages 1615-1621.e1 (June 2014) DOI: 10.1016/j.jvs.2013.12.013 Copyright © 2014 Society for Vascular Surgery Terms and Conditions

Fig 1 Identification patients in the Vascular Study Group of New England (VSGNE) for analysis. AAA, Abdominal aortic aneurysm; AP, antiplatelet (aspirin or clopidogrel); CAS, carotid artery stenting; CEA, carotid endarterectomy. Journal of Vascular Surgery 2014 59, 1615-1621.e1DOI: (10.1016/j.jvs.2013.12.013) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

Fig 2 Distribution of cases among patients undergoing primary elective operation in the Vascular Study Group of New England (VSGNE), 2005-2012. CAS, Carotid artery stenting; CEA, carotid endarterectomy; EVAR, endovascular aortic aneurysm repair; Infra, infra-inguinal artery bypass; oAAA, open abdominal aortic aneurysm repair; Supra, suprainguinal artery bypass. Journal of Vascular Surgery 2014 59, 1615-1621.e1DOI: (10.1016/j.jvs.2013.12.013) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

Fig 3 Use of optimal medication over time in the Vascular Study Group of New England (VSGNE). Optimal medical therapy, Taking antiplatelet (AP) and statin medication preoperatively and at discharge. Journal of Vascular Surgery 2014 59, 1615-1621.e1DOI: (10.1016/j.jvs.2013.12.013) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

Fig 4 a, Proportion of patients on optimal medical therapy across procedures in the Vascular Study Group of New England (VSGNE). b, Proportion of patients on optimal medical therapy across procedures in the VSGNE. AAA, Abdominal aortic aneurysm; CAS, carotid artery stenting; CEA, carotid endarterectomy; EVAR, endovascular aortic aneurysm repair; Infra, infrainguinal artery bypass; oAAA, open AAA repair; Supra, suprainguinal artery bypass. Journal of Vascular Surgery 2014 59, 1615-1621.e1DOI: (10.1016/j.jvs.2013.12.013) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

Fig 5 Variation in optimal medical therapy across Centers in the Vascular Study Group of New England (VSGNE) (2005-2012). Journal of Vascular Surgery 2014 59, 1615-1621.e1DOI: (10.1016/j.jvs.2013.12.013) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

Fig 6 Five-year survival following surgery by discharge medication status. AP, Antiplatelet medication. Journal of Vascular Surgery 2014 59, 1615-1621.e1DOI: (10.1016/j.jvs.2013.12.013) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

Supplementary Fig (online only) Variation in optimal medical therapy across Centers in the Vascular Study Group of New England (VSGNE) for centers with >100 cases (2005-2012). Journal of Vascular Surgery 2014 59, 1615-1621.e1DOI: (10.1016/j.jvs.2013.12.013) Copyright © 2014 Society for Vascular Surgery Terms and Conditions