Monthly rates of antibiotic administration. Monthly rates of antibiotic administration. The monthly rate of empirical antibiotic administration was defined as the number of infants born at ≥36 0/7 weeks’ gestation who were administered antibiotics at ≤72 hours of age divided by the total number of infants born at ≥36 0/7weeks’ gestation per calendar month. The 6-week washout period is not included. Statistical process control using p-chart methodology is shown, with the upper and lower control limits having been determined by the pre-SRC period data. The criteria for significant change in process were met after SRC implementation, with >8 consecutive data points falling below the pre-SRC mean. Miren B. Dhudasia et al. Hospital Pediatrics doi:10.1542/hpeds.2017-0180 ©2018 by American Academy of Pediatrics