Pharmacokinetics of low-molecular-weight heparin and unfractionated heparin during elective aortobifemoral bypass grafting Herman Kroneman, MD, Bert.

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Presentation transcript:

Pharmacokinetics of low-molecular-weight heparin and unfractionated heparin during elective aortobifemoral bypass grafting Herman Kroneman, MD, Bert C. Eikelboom, MD, E.A.R. Knot, MD, Pìet de Smit, MD, Theo H.N. Groenland, MD, Moniek P.M. de Maat, Hero Van Urk, MD Journal of Vascular Surgery Volume 14, Issue 2, Pages 208-214 (August 1991) DOI: 10.1067/mva.1991.29897 Copyright © 1991 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 The anti-factor Xa activity (IU/ml) before heparin (BH) and after heparin administration in patients receiving UFH or LMWH (mean ± SD). The arrow indicates an increase of UFH concentration after flushing of the aorta with UFH preparations. Journal of Vascular Surgery 1991 14, 208-214DOI: (10.1067/mva.1991.29897) Copyright © 1991 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Intraoperative FbDP plasma levels (μg/ml) before heparin administration and at the end of operation (mean ± SD). Journal of Vascular Surgery 1991 14, 208-214DOI: (10.1067/mva.1991.29897) Copyright © 1991 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions