Volume 32, Issue 3, Pages (November 2001)

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Volume 32, Issue 3, Pages 376-378 (November 2001) Glutamate and GABA Amy B MacDermott Neuron Volume 32, Issue 3, Pages 376-378 (November 2001) DOI: 10.1016/S0896-6273(01)00494-9

Figure 1 Activation of Kainate Receptors Indirectly Depresses GABA Release from Dorsal Horn Neurons Glutamate activates a presynaptic kainate receptor (KAR) causing enhanced action potential-independent GABA release by depolarization-induced opening of voltage-gated Ca2+ channels (VGCC). The GABA binds to postsynaptic GABAA receptors as well as presynaptic GABAB receptors. The action on presynaptic GABAB receptors depresses action potential-dependent GABA release Neuron 2001 32, 376-378DOI: (10.1016/S0896-6273(01)00494-9)