VOD/SOS: Aligned Education for Patients and the Interprofessional Team

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Presentation transcript:

VOD/SOS: Aligned Education for Patients and the Interprofessional Team

Overview

Case 1 Presentation

Risk Factors for VOD

Risk Factors for VOD (cont)

Case 1 Presentation (cont)

Case 1 Presentation (cont)

Case 1 Presentation (cont)

Importance of Early Recognition of VOD

Signs and Symptoms to Monitor for

Baltimore Criteria

Modified Seattle Criteria

New EBMT Criteria for Severity Grading of Suspected SOS/VOD in Adults

Case 1 Presentation (cont)

Next Steps

Contraindications to Defibrotide Therapy

Defibrotide Phase 3 Trial Design

Defibrotide Phase 3 Trial Results

AEs Associated With Defibrotide in the International Compassionate Use Program

Defibrotide for VOD Pooled Analysis of Survival Reported at ASH 2018

Analysis 1: Before/After Specific Days

Analysis 2: On Specific Days

AEs With Defibrotide Use

Supportive Measures

Other Supportive Measures

Case 1 Conclusion

Case 2 Presentation

Case 2 Presentation (cont)

Case 2 Presentation (cont)

Key Take-Aways

Abbreviations

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