Skeeter syndrome Journal of Allergy and Clinical Immunology

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Presentation transcript:

Skeeter syndrome Journal of Allergy and Clinical Immunology F.Estelle R. Simons, MD, FRCPC, Zhikang Peng, MD Journal of Allergy and Clinical Immunology Volume 104, Issue 3, Pages 705-707 (September 1999) DOI: 10.1016/S0091-6749(99)70348-9 Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 1 At age 21 months, this child was bitten just below the right eye by a mosquito. The insect was brushed away. Swelling at the site of the bite began within 1 hour and was accompanied by redness and warmth. The eye rapidly swelled shut and remained swollen for a week. Blood culture was negative. Later, during the summer, similar reactions occurred after mosquito bites on the lower leg and the ear. The photograph was taken by the child’s mother. Journal of Allergy and Clinical Immunology 1999 104, 705-707DOI: (10.1016/S0091-6749(99)70348-9) Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 2 A, Significantly elevated serum concentrations of A vexans saliva–specific IgE, IgG1, IgG3, and IgG4 were found in children with skeeter syndrome (mosquito bite–induced large local inflammatory reaction originally diagnosed as cellulitis) in contrast to age-matched control children. IgG2 was not detectable. B, Seasonal variation in A vexans saliva–specific IgE, IgG1, IgG3, and IgG4 in children with skeeter syndrome. Antibody concentrations declined significantly during the cold winter months when no exposure to mosquitoes occurred. Journal of Allergy and Clinical Immunology 1999 104, 705-707DOI: (10.1016/S0091-6749(99)70348-9) Copyright © 1999 Mosby, Inc. Terms and Conditions