The Life Cycle of a Filamentous Phage

The Genome of a Filamentous Phage

The Intergenic Region with the + and – Strand Origins

Filamentous Phage DNA Replication

Assembly of the Filamentous Phage at the Bacterial Cell Surface

Distinction between Ff and ϕX 174 Pages

Plasmid Replication – the ColE1 Replicon

The ColE1 Origin of Replication and the Structure of the RNA Primers

The Interaction of the RNA I and RNA II Primers

The Requirement for Topoisomerases

The Action of Gyrase ( aTopoisomerase II)

Properties of Type I and Type II Topoisomerases

The Origins of Replication of Enteric Bacterial Chromosomes

Initiation of DNA Replication at the E.Coli Origin

DNA Replication Fork in E.coli