Prehypertension and Incidence of ESRD: A Systematic Review and Meta-analysis Yuli Huang, MD, Xiaoyan Cai, MD, Jianyu Zhang, MD, Weiyi Mai, MD, PhD, Sheng.

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Prehypertension and Incidence of ESRD: A Systematic Review and Meta-analysis Yuli Huang, MD, Xiaoyan Cai, MD, Jianyu Zhang, MD, Weiyi Mai, MD, PhD, Sheng Wang, MD, Yunzhao Hu, MD, PhD, Hao Ren, MD, Dingli Xu, MD American Journal of Kidney Diseases Volume 63, Issue 1, Pages 76-83 (January 2014) DOI: 10.1053/j.ajkd.2013.07.024 Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Flow of selection for studies through review. Abbreviations: BP, blood pressure; CIs, confidence intervals; CKD, chronic kidney disease; ESRD, end-stage renal disease; RRs, relative risks. American Journal of Kidney Diseases 2014 63, 76-83DOI: (10.1053/j.ajkd.2013.07.024) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Forest plot of comparison: prehypertension versus optimal blood pressure, outcome: end-stage renal disease. Abbreviations: BP, blood pressure; CI, confidence interval; CNHS, China National Hypertension Survey; HUNT I, the first Health Study in Nord-Trøndelag; MRFIT, Multiple Risk Factor Intervention Trial; NA, not available; OKIDS, the Okinawa Dialysis Study. American Journal of Kidney Diseases 2014 63, 76-83DOI: (10.1053/j.ajkd.2013.07.024) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions

Figure 3 Forest plot of comparison: subgroup analyses of primary outcomes conducted according to the level of blood pressure (BP; low-range prehypertension vs high-range prehypertension). Abbreviations: CI, confidence interval; MRFIT, Multiple Risk Factor Intervention Trial; NA, not available; OKIDS, the Okinawa Dialysis Study. American Journal of Kidney Diseases 2014 63, 76-83DOI: (10.1053/j.ajkd.2013.07.024) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions