Fig. 6 Malaria and l-arginine induce changes in the expression of inflammatory and angiogenic mediators in placental tissue by reverse transcription PCR.

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Fig. 6 Malaria and l-arginine induce changes in the expression of inflammatory and angiogenic mediators in placental tissue by reverse transcription PCR. Malaria and l-arginine induce changes in the expression of inflammatory and angiogenic mediators in placental tissue by reverse transcription PCR. (A to H) C5 (A), C5ar (B), Icam-1 (C), Tie-2 (D), Ang-1 (E), Ang-2 (F), Vegf-a (G), and Flt-1 (VEGF receptor) (H) in uninfected (UI) vehicle control–treated (Veh) dams (n = 12), uninfected (UI) l-arginine–treated (l-Arg) dams (n = 12), malaria-infected (PbA) vehicle control–treated dams (n = 12), and malaria-infected l-arginine–treated dams (n = 12). Box plots depict median, and interquartile range with whiskers depicts maximum and minimum values. Results of one-way ANOVA and Tukey post test; *P < 0.05, **P < 0.01, and ***P < 0.001. Chloe R. McDonald et al., Sci Transl Med 2018;10:eaan6007 Published by AAAS