Fatigue in Children with Cancer at the End of Life

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Fatigue in Children with Cancer at the End of Life Christina K. Ullrich, MD, MPH, Veronica Dussel, MD, MPH, Joanne M. Hilden, MD, Jan W. Sheaffer, BA, Caron L. Moore, RN, MSW, Charles B. Berde, MD, PhD, Joanne Wolfe, MD, MPH Journal of Pain and Symptom Management Volume 40, Issue 4, Pages 483-494 (October 2010) DOI: 10.1016/j.jpainsymman.2010.02.020 Copyright © 2010 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 1 Conceptual model of fatigue in children in the last month of life. aFactors variably associated with fatigue in other pediatric cancer and adult advanced cancer populations. Journal of Pain and Symptom Management 2010 40, 483-494DOI: (10.1016/j.jpainsymman.2010.02.020) Copyright © 2010 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 2 Conceptual model integrating clinical factors associated with fatigue, pathophysiological processes that may mediate such associations, and potential interventions to ameliorate fatigue. Journal of Pain and Symptom Management 2010 40, 483-494DOI: (10.1016/j.jpainsymman.2010.02.020) Copyright © 2010 U.S. Cancer Pain Relief Committee Terms and Conditions