Ubiquitin-Proteasome: Pallbearer Carries the Deceased to the Grave

Slides:

Advertisements

Similar presentations

Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer Shaun K. Olsen, Christopher D. Lima Molecular Cell Volume 49, Issue 5, Pages.

Advertisements

How T Cells Earn the Follicular Rite of Passage Carola G. Vinuesa, Jason G. Cyster Immunity Volume 35, Issue 5, Pages (November 2011) DOI: /j.immuni

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

T-bet+ Treg Cells Undergo Abortive Th1 Cell Differentiation due to Impaired Expression of IL-12 Receptor β2 Meghan A. Koch, Kerri R. Thomas, Nikole R.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Origins of Metastatic Traits Sakari Vanharanta, Joan Massagué Cancer Cell Volume 24, Issue 4, Pages (October 2013) DOI: /j.ccr

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet

Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages (October.

Decision Making as a Window on Cognition Michael N. Shadlen, Roozbeh Kiani Neuron Volume 80, Issue 3, Pages (October 2013) DOI: /j.neuron

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

The Transcription Factor Foxo1 Controls Central-Memory CD8+ T Cell Responses to Infection Myoungjoo V. Kim, Weiming Ouyang, Will Liao, Michael Q. Zhang,

Lung Natural Helper Cells Are a Critical Source of Th2 Cell-Type Cytokines in Protease Allergen-Induced Airway Inflammation Timotheus Y.F. Halim, Ramona.

Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells Julien Seneschal, Rachael A. Clark,

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages (April.

Lipin-1 Regulates Autophagy Clearance and Intersects with Statin Drug Effects in Skeletal Muscle Peixiang Zhang, M. Anthony Verity, Karen Reue Cell Metabolism.

SRC-3 Coactivator Functional Lifetime Is Regulated by a Phospho-Dependent Ubiquitin Time Clock Ray-Chang Wu, Qin Feng, David M. Lonard, Bert W. O'Malley.

CDK Inhibitors: Cell Cycle Regulators and Beyond Arnaud Besson, Steven F. Dowdy, James M. Roberts Developmental Cell Volume 14, Issue 2, Pages

Lung Airway-Surveilling CXCR3hi Memory CD8+ T Cells Are Critical for Protection against Influenza A Virus Bram Slütter, Lecia L. Pewe, Susan M. Kaech,

Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm Thierry Soussi, Klas G. Wiman Cancer Cell Volume 12, Issue 4, Pages (October.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.

Human-Hemato-Lymphoid-System Mice: Opportunities and Challenges

HIV-1 Latency by Transition

Volume 1, Issue 1, Pages (June 2007)

An Activation Marker Finds a Function

Gut Nod2 Calls the Bone Marrow for Monocyte Reinforcements

Toll-like Receptors Keep Antigen Sorting on the Right Track

Chronic Infections Capture Little Attention of the Masses

A Flt3L Encounter: mTOR Signaling in Dendritic Cells

Autophagy: Paying Charon's Toll

Maintaining Hematopoietic Stem Cells in the Vascular Niche

CD4 Helpers Put Tissue-Resident Memory Cells in Their Place

Unraveling the Pros and Cons of Interferon-γ Gene Regulation

PU.1 Takes Control of the Dendritic Cell Lineage

Thymic Selection: To Thine Own Self Be True

IL-2: Change Structure … Change Function

Arming Treg Cells at the Inflammatory Site

MicroRNAs in Tfh Cells: Micromanaging Inflammaging

Proteaphagy—Selective Autophagy of Inactive Proteasomes

Chronic Infections Capture Little Attention of the Masses

The Dynamic Cytokine Niche

Michelle A. Linterman, Alice E. Denton Immunity

Proteasomes: Machines for All Reasons

Keeping Transcriptional Activators under Control

Drugging Chromatin in Cancer: Recent Advances and Novel Approaches

Blood Tfh Cells Come with Colors

Antigen-Presenting Cells: Professionals and amateurs

A Prescription for Human Immunology

Ubiquitin Makes Its Mark on Immune Regulation

Death in the CNS: Six-Microns-Under

Volume 30, Issue 2, Pages (February 2009)

Michelle A. Linterman, Alice E. Denton Immunity

MicroRNA-155 Function in B Cells

Taking a Toll Road to Better Vaccines

Recycling Endosomes and TLR Signaling— The Rab11 GTPase Leads the Way

Immune Cells Exploit a Neural Circuit to Enter the CNS

t Testing the Immune System

Volume 163, Issue 2, (October 2015)

S-Nitrosylation at the Interface of Autophagy and Disease

At 17, In-10's Passion Need Not Inflame

Oxygenated Lipids: A Mode to WiPE Out Inflammation?

Volume 27, Issue 5, Pages (November 2007)

Marking Emerging β- and γδ-Selected T Cells

A “Big Data” View of the Tumor “Immunome”

IL-9 by INFERence Immunity

Presentation transcript:

Ubiquitin-Proteasome: Pallbearer Carries the Deceased to the Grave Dominique Ferrandon Immunity Volume 27, Issue 4, Pages 541-544 (October 2007) DOI: 10.1016/j.immuni.2007.10.003 Copyright © 2007 Elsevier Inc. Terms and Conditions

Figure 1 Model of Apoptotic Cell Clearance in D. melanogaster The ubiquitin-proteasome system may control the stability of an inhibitor, X, that may regulate one or multiple steps required for efficient engulfment of apoptotic cells. See text for further discussion. CQM, Croquemort; DRP, Draper; Ub, ubiquitin. Immunity 2007 27, 541-544DOI: (10.1016/j.immuni.2007.10.003) Copyright © 2007 Elsevier Inc. Terms and Conditions