Characterization of the early pharmacodynamic profile of oral methadone for cancer- related breakthrough pain: a pilot study Kim Fisher, PhD, Carla Stiles,

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Presentation transcript:

Characterization of the early pharmacodynamic profile of oral methadone for cancer- related breakthrough pain: a pilot study Kim Fisher, PhD, Carla Stiles, RN, Neil A. Hagen, MD, FRCPC (Neurology) Journal of Pain and Symptom Management Volume 28, Issue 6, Pages 619-625 (December 2004) DOI: 10.1016/j.jpainsymman.2004.03.003 Copyright © 2004 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 1 Mean changes in pain intensity from baseline across time, measured by numeric rating scale (0=no pain, 10=worst pain possible) completed at 10-minute intervals following treatment with patients' usual ‘rescue’ opioid or optimal dose of oral methadone HCl. Journal of Pain and Symptom Management 2004 28, 619-625DOI: (10.1016/j.jpainsymman.2004.03.003) Copyright © 2004 U.S. Cancer Pain Relief Committee Terms and Conditions