The MECT1-MAML2 Gene Fusion and Benign Warthin's Tumor

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The MECT1-MAML2 Gene Fusion and Benign Warthin's Tumor Marta Winnes, Fredrik Enlund, Joachim Mark, Göran Stenman The Journal of Molecular Diagnostics Volume 8, Issue 3, Pages 394-396 (July 2006) DOI: 10.2353/jmoldx.2006.060020 Copyright © 2006 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 1 A: FISH analysis of a paraffin section of the WAT demonstrating split MAML2 signals (separation of one green and one red signal) in the tumor cells (TC) lining the cystic spaces. In contrast, no rearrangements of MAML2 are detected in the lymphoid cells (LC). B: Immunostaining of the MECT1-MAML2 fusion protein. Note the predominant nuclear staining of the tumor cells lining the cystic spaces of the tumor. The surrounding lymphoid stroma is mainly negative. The Journal of Molecular Diagnostics 2006 8, 394-396DOI: (10.2353/jmoldx.2006.060020) Copyright © 2006 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions