Reversing Time: Origin of Telomerase

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Reversing Time: Origin of Telomerase Toru M Nakamura, Thomas R Cech  Cell  Volume 92, Issue 5, Pages 587-590 (March 1998) DOI: 10.1016/S0092-8674(00)81123-X

Figure 1 Reverse Transcriptase Trees An unrooted tree of reverse transcriptases (A), and trees rooted with RRPs (B) and with prokaryotic and organellar retroelements (C). The arrow in (C) indicates where RRPs would fit if they are not removed from the tree. The length of each box corresponds to the most divergent element within that box. Methods are cited in Nakamura et al. 1997. Cell 1998 92, 587-590DOI: (10.1016/S0092-8674(00)81123-X)

Figure 2 Proposed Origin of RTs, Including Telomerase The proposed origin of RTs is superimposed on a scheme for the origin of life and the evolution of species (Gupta and Golding 1996). Question marks denote some of the points of uncertainty or alternative possibilities. Cell 1998 92, 587-590DOI: (10.1016/S0092-8674(00)81123-X)