Clinical validation of embryo culture and selection by morphokinetic analysis: a randomized, controlled trial of the EmbryoScope Irene Rubio, Ph.D.,

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Presentation transcript:

Clinical validation of embryo culture and selection by morphokinetic analysis: a randomized, controlled trial of the EmbryoScope Irene Rubio, Ph.D., Arancha Galán, Ph.D., Zaloa Larreategui, Ph.D., Fernando Ayerdi, Ph.D., Jose Bellver, M.D., Javier Herrero, Ph.D., Marcos Meseguer, Ph.D. Fertility and Sterility Volume 102, Issue 5, Pages 1287-1294.e5 (November 2014) DOI: 10.1016/j.fertnstert.2014.07.738 Copyright © 2014 The Authors Terms and Conditions

Supplemental Figure 1 Morphokinetic decision tree algorithm used for embryo selection. For the division to five cells, a shorthand notation of t5 is used; we defined the duration of the second cell cycle (cc2) as the time from division to a two-blastomere embryo until division to a three-blastomere embryo: cc2 = t3 − t2. We defined the second synchrony (s2) as the duration of the division transition from a two-blastomere embryo to a four-blastomere embryo: s2 = t4 − t3. We defined direct cleavage as those cases in which cc2 was lower than 5 hours. The time of all events is expressed as hours after ICSI microinjection. Fertility and Sterility 2014 102, 1287-1294.e5DOI: (10.1016/j.fertnstert.2014.07.738) Copyright © 2014 The Authors Terms and Conditions

Supplemental Figure 2 Patient flow chart presentation. Number of patients and descriptions of patients are included in every box. Fertility and Sterility 2014 102, 1287-1294.e5DOI: (10.1016/j.fertnstert.2014.07.738) Copyright © 2014 The Authors Terms and Conditions