Phillip S. Naimo, MD, David McGiffin, MD, FRACS, Igor E

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Lost in translation The Journal of Thoracic and Cardiovascular Surgery

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Presentation transcript:

Aspirin resistance in the era of personalized medicine: Should we not take it personally? Phillip S. Naimo, MD, David McGiffin, MD, FRACS, Igor E. Konstantinov, MD, PhD, FRACS The Journal of Thoracic and Cardiovascular Surgery Volume 150, Issue 6, Pages e99-e100 (December 2015) DOI: 10.1016/j.jtcvs.2015.09.049 Copyright © 2015 Terms and Conditions

Figure 1 Schematic impact of low-dose aspirin on platelet activation and aggregation. Aspirin in low doses may leave some COX-2, production of which may significantly increase in inflammatory conditions, uninhibited, and result in increased platelet activation and aggregation. COX, Cyclooxygenase. The Journal of Thoracic and Cardiovascular Surgery 2015 150, e99-e100DOI: (10.1016/j.jtcvs.2015.09.049) Copyright © 2015 Terms and Conditions

Schematic of aspirin impact on platelets. The Journal of Thoracic and Cardiovascular Surgery 2015 150, e99-e100DOI: (10.1016/j.jtcvs.2015.09.049) Copyright © 2015 Terms and Conditions