Proceedings of the Summit on Environmental Challenges to Reproductive Health and Fertility: executive summary  Tracey J. Woodruff, Ph.D., M.P.H., Alison Carlson, Jackie M. Schwartz, M.P.H., Linda C. Giudice, M.D., Ph.D.  Fertility and Sterility  Volume 89, Issue 2, Pages 281-300 (February 2008) DOI: 10.1016/j.fertnstert.2007.10.002 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Key definitions for environmental reproductive health. Fertility and Sterility 2008 89, 281-300DOI: (10.1016/j.fertnstert.2007.10.002) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Windows of susceptibility to environmental insults [adapted from (253)]. Fertility and Sterility 2008 89, 281-300DOI: (10.1016/j.fertnstert.2007.10.002) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 3 Schematic diagram to illustrate how dysgenesis of the early fetal testis is thought to lead to abnormalities of somatic cell function, resulting in hormonal changes and the downstream disorders that comprise testicular dysgenesis syndrome (TDS). The central role of testosterone is highlighted by the blue boxes. Dashed lines show pathways that are hypothesized but unproven (Adapted from Sharpe and Skakkebaek [68]). Abbreviations: PTMC = peritubular myoid cell; Insl3 = insulin-like factor 3; AMH = anti-müllerian hormone; CIS = carcinoma-in-situ; SCO = Sertoli cell only. Fertility and Sterility 2008 89, 281-300DOI: (10.1016/j.fertnstert.2007.10.002) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions