Farkas Vánky, MD, Mats Broquist, MD, PhD, Rolf Svedjeholm, MD, PhD

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Presentation transcript:

Addition of a Thiazide: An Effective Remedy for Furosemide Resistance After Cardiac Operations Farkas Vánky, MD, Mats Broquist, MD, PhD, Rolf Svedjeholm, MD, PhD The Annals of Thoracic Surgery Volume 63, Issue 4, Pages 993-997 (April 1997) DOI: 10.1016/S0003-4975(96)01217-9

Fig. 1 Diuretic requirements in 210 adult patients after cardiac operations illustrated by the highest total dose of furosemide in milligrams (intravenous and oral doses included) given over 24 hours at some time during the postoperative course. (80/HT+A = number of patients who in addition to furosemide ≥80 mg required 50 mg hydrochlorothiazide and 5 mg amiloride.) The Annals of Thoracic Surgery 1997 63, 993-997DOI: (10.1016/S0003-4975(96)01217-9)

Fig. 2 Average change in weight postoperatively in the hydrochlorothiazide plus amiloride (HT+A) group after furosemide ≥80 mg orally (F80) and the addition of 50 mg hydrochlorothiazide and 5 mg amiloride to furosemide. Because weight was not recorded in the intensive care unit, the weight curve does not give a representative picture of the change in weight during the early postoperative course. Statistically significant change compared with previous observation: ∗p < 0.05; ∗∗p < 0.01. The Annals of Thoracic Surgery 1997 63, 993-997DOI: (10.1016/S0003-4975(96)01217-9)