Impact of Adverse Event Solicitation on the Safety Profile of SQ House Dust Mite Sublingual Immunotherapy Tablet  Hendrik Nolte, MD, PhD, David I. Bernstein,

Slides:



Advertisements
Similar presentations
Reducing relative humidity to control the house dust mite Dermatophagoides farinae Larry G. Arlian, PhD, Jacqueline S. Neal, BS, DiAnn L. Vyszenski-Moher,
Advertisements

Double-Blind Placebo-Controlled Trial of Dapsone in Antihistamine Refractory Chronic Idiopathic Urticaria  Matt Morgan, MD, Andrew Cooke, MD, Laura Rogers,
The Journal of Allergy and Clinical Immunology: In Practice
Advances in Diagnosing Peanut Allergy
Treatment effect of sublingual immunotherapy tablets and pharmacotherapies for seasonal and perennial allergic rhinitis: Pooled analyses  Stephen R. Durham,
Aleena Banerji, MD, Kimberly G. Blumenthal, MD, MSc, Kenneth H
Treatment effect of sublingual immunotherapy tablets and pharmacotherapies for seasonal and perennial allergic rhinitis: Pooled analyses  Stephen R. Durham,
Optimal dose, efficacy, and safety of once-daily sublingual immunotherapy with a 5– grass pollen tablet for seasonal allergic rhinitis  Alain Didier, MD,
Vitamin D Insufficiency and Asthma in a US Nationwide Study
Randomized controlled trial of a ragweed allergy immunotherapy tablet in North American and European adults  Peter S. Creticos, MD, Jennifer Maloney,
Chronic rhinosinusitis: Potential new use for topical sulfasalazine
Complementary and Alternative Medicine in Allergy-Immunology: More Information is Needed  Leonard Bielory, MD  The Journal of Allergy and Clinical Immunology:
Fanny Legrand, PhD, PharmD, Amy D. Klion, MD 
Dennis K. Ledford, MD, Sally Wenzel, MD 
Network Meta-analysis Shows Commercialized Subcutaneous and Sublingual Grass Products Have Comparable Efficacy  Harold Nelson, MD, Shannon Cartier, MSc,
Shyam Joshi, MD, David A. Khan, MD 
The Effect of Tiotropium in Symptomatic Asthma Despite Low- to Medium-Dose Inhaled Corticosteroids: A Randomized Controlled Trial  Pierluigi Paggiaro,
Desensitization to Chemotherapeutic Agents
Intramuscular Versus Intravenous Immunoglobulin Replacement Therapy and Measurement of Immunoglobulin Levels During Immunoglobulin Replacement Therapy 
Practice Notes from the AAAI
A Multicenter Observational Study of US Adults with Acute Asthma: Who Are the Frequent Users of the Emergency Department?  Kohei Hasegawa, MD, MPH, Ashley.
An Infant with Atopic Dermatitis and Itching After Ingestion of Milk
Comparative Effectiveness of Budesonide-Formoterol Combination and Fluticasone- Salmeterol Combination for Asthma Management: A United States Retrospective.
Hendrik Nolte, MD, PhD, David I
Asthma Exacerbations and Triggers in Children in TENOR: Impact on Quality of Life  Bradley E. Chipps, MD, Tmirah Haselkorn, PhD, Karin Rosén, MD, PhD,
Reactions to Rituximab in an Outpatient Infusion Center: A 5-Year Review  Amy S. Levin, MD, Iris M. Otani, MD, Timothy Lax, MD, Ephraim Hochberg, MD, Aleena.
Validation of the Pregnancy Asthma Control Test
Reply Journal of Allergy and Clinical Immunology
Mechanism-Based Strategies for the Management of Autoimmunity and Immune Dysregulation in Primary Immunodeficiencies  Jolan E. Walter, MD, PhD, Jocelyn.
Advances in Diagnosing Peanut Allergy
Timothy J. Craig, DO, H. Henry Li, MD, Marc Riedl, MD, Jonathan A
Nonadherence to Asthma Treatment: Getting Unstuck
Thys van der Molen, MD, PhD, Monica Fletcher, MSc, David Price, FRCGP 
Practice Notes from the AAAAI
Penicillin Skin Testing Is a Safe and Effective Tool for Evaluating Penicillin Allergy in the Pediatric Population  Stephanie J. Fox, MD, Miguel A. Park,
Reply Journal of Allergy and Clinical Immunology
Phillip Lieberman, MD, Michael Tankersley, MD 
The Emperor Has No Symptoms: The Risks of a Blanket Approach to Using Epinephrine Autoinjectors for All Allergic Reactions  Paul J. Turner, FRACP, PhD,
Effects of Mometasone, Fluticasone, and Montelukast on Bone Mineral Density in Adults with Asthma  Jorge Maspero, MD, Vibeke Backer, DMSci, MD, Ruji Yao,
News & Notes Journal of Allergy and Clinical Immunology
Double-Blind Placebo-Controlled Trial of Dapsone in Antihistamine Refractory Chronic Idiopathic Urticaria  Matt Morgan, MD, Andrew Cooke, MD, Laura Rogers,
Baboon Syndrome Associated with Ampicillin Sulbactam
The Management of Eosinophilic Esophagitis
Phillip Lieberman, MD, David Golden, MD 
Sequential Treatment Initiation with Timothy Grass and Ragweed Sublingual Immunotherapy Tablets Followed by Simultaneous Treatment Is Well Tolerated 
Anaphylactic Reaction to White-Faced Hornet Sting and Elevated Baseline (Asymptomatic) Serum Tryptase  Phillip Lieberman, MD, Lawrence B. Schwartz, MD,
Efficacy of house dust mite sublingual immunotherapy tablet in North American adolescents and adults in a randomized, placebo-controlled trial  Hendrik.
Justin R. Chen, MD, Brett L. Buchmiller, MD, David A. Khan, MD 
International Study of Risk-Mitigating Factors and In-Flight Allergic Reactions to Peanut and Tree Nut  Matthew Greenhawt, MD, MBA, MSc, Fiona MacGillivray,
The editors' choice Journal of Allergy and Clinical Immunology
News Beyond Our Pages Journal of Allergy and Clinical Immunology
Real-world attitudes among allergists/immunologists regarding oral immunotherapy and preferred terminology  Bradley E. Chipps, MD, Christina E. Ciaccio,
Sharon Seth, MD, David A. Khan, MD 
Cephalosporin Side Chain Cross-reactivity
News & Notes Journal of Allergy and Clinical Immunology
News Beyond Our Pages Journal of Allergy and Clinical Immunology
Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment
Impact of Adverse Event Solicitation on the Safety Profile of SQ House Dust Mite Sublingual Immunotherapy Tablet  Hendrik Nolte, MD, PhD, David I. Bernstein,
Reply The Journal of Allergy and Clinical Immunology: In Practice
News Beyond Our Pages Journal of Allergy and Clinical Immunology
Practice Notes from the AAAI
Efficacy and safety of the SQ house dust mite sublingual immunotherapy tablet in Japanese adults and adolescents with house dust mite–induced allergic.
News Beyond Our Pages Journal of Allergy and Clinical Immunology
Footnotes1 Journal of Allergy and Clinical Immunology
Pedro Giavina-Bianchi, MD, PhD, Shih-Wen Huang, MD 
News Beyond Our Pages Journal of Allergy and Clinical Immunology
Effect of grass sublingual tablet immunotherapy is similar in children and adults: A Bayesian approach to design pediatric sublingual immunotherapy trials 
News & Notes Journal of Allergy and Clinical Immunology
News Beyond Our Pages Journal of Allergy and Clinical Immunology
News Beyond Our Pages Journal of Allergy and Clinical Immunology
Presentation transcript:

Impact of Adverse Event Solicitation on the Safety Profile of SQ House Dust Mite Sublingual Immunotherapy Tablet  Hendrik Nolte, MD, PhD, David I. Bernstein, MD, Gordon L. Sussman, MD, Bodil Svanholm Fogh, MSc, Susan Lu, PharmD, Bernt Husøy, MD, Harold S. Nelson, MD  The Journal of Allergy and Clinical Immunology: In Practice  Volume 6, Issue 6, Pages 2081-2086.e1 (November 2018) DOI: 10.1016/j.jaip.2018.01.037 Copyright © 2018 ALK Abelló A/S Terms and Conditions

Figure 1 Placebo-subtracted frequencies of local site reactions in trials that solicited or did not solicit the daily occurrence of each reaction. AE, Adverse event. The Journal of Allergy and Clinical Immunology: In Practice 2018 6, 2081-2086.e1DOI: (10.1016/j.jaip.2018.01.037) Copyright © 2018 ALK Abelló A/S Terms and Conditions