Michael Argenziano, MDa, David A

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Presentation transcript:

Inhaled Nitric Oxide Is Not A Myocardial Depressant In A Porcine Model Of Heart Failure Michael Argenziano, MDa, David A. Dean, MDa, Nader Moazami, MDa, Daniel J. Goldstein, MDa, Eric A. Rose, MDa, Henry M. Spotnitz, MDa, Daniel Burkhoff, MDb, Mehmet C. Oz, MDa, Marc L. Dickstein, MDc The Journal of Thoracic and Cardiovascular Surgery Volume 115, Issue 3, Pages 700-708 (March 1998) DOI: 10.1016/S0022-5223(98)70336-8 Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 1 Representative preload-varying pressure-volume diagram. P, Pressure; V, volume. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 700-708DOI: (10.1016/S0022-5223(98)70336-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 2 Echocardiogram demonstrating four-chamber dilatation. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 700-708DOI: (10.1016/S0022-5223(98)70336-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 3 Effects of inhaled nitric oxide (NO) on pulmonary vascular resistance (PVR). The Journal of Thoracic and Cardiovascular Surgery 1998 115, 700-708DOI: (10.1016/S0022-5223(98)70336-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 4 Effects of inhaled nitric oxide (NO) on pulmonary artery pressure (PAP), left ventricular end-diastolic pressure (LVEDP), and transplumonary gradient (TPG). The Journal of Thoracic and Cardiovascular Surgery 1998 115, 700-708DOI: (10.1016/S0022-5223(98)70336-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 5 Representative end-systolic pressure-volume relationship plot. ESP, End-systolic pressure; ESV, end-systolic volume; NO, nitric oxide. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 700-708DOI: (10.1016/S0022-5223(98)70336-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 6 Representative preload-recruitable stroke work plot. SW, Stroke work; EDV, end-diastolic volume; NO, nitric oxide. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 700-708DOI: (10.1016/S0022-5223(98)70336-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 7 Comparison of V10 values derived from the end-diastolic pulmonary vascular resistance. NO, Nitric oxide. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 700-708DOI: (10.1016/S0022-5223(98)70336-8) Copyright © 1998 Mosby, Inc. Terms and Conditions