Effectiveness of diclofenac versus paracetamol in knee osteoarthritis: a randomised controlled trial in primary care by Saskia PJ Verkleij, Pim AJ Luijsterburg,

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Effectiveness of diclofenac versus paracetamol in knee osteoarthritis: a randomised controlled trial in primary care by Saskia PJ Verkleij, Pim AJ Luijsterburg, Sten P Willemsen, Bart W Koes, Arthur M Bohnen, and Sita MA Bierma-Zeinstra BJGP Volume 65(637):e530-e537 July 26, 2015 ©2015 by British Journal of General Practice

Flowchart of the study. Flowchart of the study. ACR = American College of Rheumatology. NSAIDs = non-steroidal anti-inflammatory drugs. Saskia PJ Verkleij et al. Br J Gen Pract 2015;65:e530-e537 ©2015 by British Journal of General Practice

Mean daily measured knee pain severity of the paracetamol and diclofenac group over a period of 4-weeks follow-up. Mean daily measured knee pain severity of the paracetamol and diclofenac group over a period of 4-weeks follow-up. NRS = Numeric Rating Scale. Saskia PJ Verkleij et al. Br J Gen Pract 2015;65:e530-e537 ©2015 by British Journal of General Practice

Mean medication intake of the paracetamol and diclofenac group over a period of 4-weeks follow-up. aThe daily dose of diclofenac was converted (for example, total use of 150 mg of diclofenac per day was converted to 3000 mg). Mean medication intake of the paracetamol and diclofenac group over a period of 4-weeks follow-up. aThe daily dose of diclofenac was converted (for example, total use of 150 mg of diclofenac per day was converted to 3000 mg). Saskia PJ Verkleij et al. Br J Gen Pract 2015;65:e530-e537 ©2015 by British Journal of General Practice