Kristina Rueter, MD, Anderson P

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Presentation transcript:

Direct infant UV light exposure is associated with eczema and immune development Kristina Rueter, MD, Anderson P. Jones, PhD, Aris Siafarikas, MD, Ee-Mun Lim, MD, PhD, Natasha Bear, MBiostats, Paul S. Noakes, PhD, Susan L. Prescott, MD, PhD, Debra J. Palmer, PhD Journal of Allergy and Clinical Immunology Volume 143, Issue 3, Pages 1012-1020.e2 (March 2019) DOI: 10.1016/j.jaci.2018.08.037 Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Journal of Allergy and Clinical Immunology 2019 143, 1012-1020 Journal of Allergy and Clinical Immunology 2019 143, 1012-1020.e2DOI: (10.1016/j.jaci.2018.08.037) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Study flow of participants. Journal of Allergy and Clinical Immunology 2019 143, 1012-1020.e2DOI: (10.1016/j.jaci.2018.08.037) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Scatter plots of cytokine (IL-2 and IL-1β production to TLR (TLR2/6, TLR4, and TLR7/8) ligands and OVA comparison between the intervention vitamin D–supplemented and placebo groups. Journal of Allergy and Clinical Immunology 2019 143, 1012-1020.e2DOI: (10.1016/j.jaci.2018.08.037) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Scatter plots of cytokine (IL-2, GM-CSF, eotaxin, and RANTES) production to TLR (TLR2/6, TLR4 and TLR7/8) ligands in accordance with UV light exposure from 0 to 3 months of age. Journal of Allergy and Clinical Immunology 2019 143, 1012-1020.e2DOI: (10.1016/j.jaci.2018.08.037) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions